Changes in the brain during long-term follow-up after liver transplantation
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00055831" target="_blank" >RIV/00023001:_____/12:00055831 - isvavai.cz</a>
Výsledek na webu
<a href="http://onlinelibrary.wiley.com/doi/10.1002/jmri.23599/abstract;jsessionid=DE9D7588F719B27089FDD7B2D68285A9.d03t04" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/jmri.23599/abstract;jsessionid=DE9D7588F719B27089FDD7B2D68285A9.d03t04</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jmri.23599" target="_blank" >10.1002/jmri.23599</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Changes in the brain during long-term follow-up after liver transplantation
Popis výsledku v původním jazyce
PURPOSE: To examine changes in the brain before liver transplantation caused by the accumulation of paramagnetic ion deposits and to investigate recovery after liver transplantation over a long-term horizon. MATERIALS AND METHODS: Fifteen patients indicated for liver transplantation, 26 patients up to 2 years after, and 40 patients 8-15 years after liver transplantation were subjected to MR relaxometry. T(1) and T(2) relaxation times in the basal ganglia, thalamus, and white matter were evaluated. RESULTS: Relaxometry revealed a shortening of the relaxation times due to the deposition of paramagnetic ions in the basal ganglia before liver transplantation (P < 0.05), complete normalization of the relaxation times shortly after transplantation in the globus pallidus and caudate nucleus, and partial recovery of T(2) in the putamen. Relaxation times remained stable even 15 years posttransplantation. Increased relaxation times posttransplantation were found in the white matter and thalamus.
Název v anglickém jazyce
Changes in the brain during long-term follow-up after liver transplantation
Popis výsledku anglicky
PURPOSE: To examine changes in the brain before liver transplantation caused by the accumulation of paramagnetic ion deposits and to investigate recovery after liver transplantation over a long-term horizon. MATERIALS AND METHODS: Fifteen patients indicated for liver transplantation, 26 patients up to 2 years after, and 40 patients 8-15 years after liver transplantation were subjected to MR relaxometry. T(1) and T(2) relaxation times in the basal ganglia, thalamus, and white matter were evaluated. RESULTS: Relaxometry revealed a shortening of the relaxation times due to the deposition of paramagnetic ions in the basal ganglia before liver transplantation (P < 0.05), complete normalization of the relaxation times shortly after transplantation in the globus pallidus and caudate nucleus, and partial recovery of T(2) in the putamen. Relaxation times remained stable even 15 years posttransplantation. Increased relaxation times posttransplantation were found in the white matter and thalamus.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FJ - Chirurgie včetně transplantologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NS10523" target="_blank" >NS10523: Dlouhodobý vývoj morfologie a metabolizmu mozku po transplantaci jater</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of magnetic resonance imaging
ISSN
1053-1807
e-ISSN
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Svazek periodika
35
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
6
Strana od-do
1332-1337
Kód UT WoS článku
000304035100009
EID výsledku v databázi Scopus
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