Postprandial triglyceridemia after single dose of alcohol in healthy young men

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F13%3A00058475" target="_blank" >RIV/00023001:_____/13:00058475 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0939475311001311" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0939475311001311</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.numecd.2011.05.003" target="_blank" >10.1016/j.numecd.2011.05.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Postprandial triglyceridemia after single dose of alcohol in healthy young men

Popis výsledku v původním jazyce

BACKGROUND AND AIMS: Moderate alcohol consumption provides protection against cardiovascular disease primarily due to increase of HDL-cholesterol. However, it also has some adverse effects on metabolism of triglycerides (TG). Therefore, we addressed thequestion how a single dose of alcohol affects postprandial lipemia and activities of two enzymes playing a critical role in regulation of triglyceridemia, lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL). METHODS AND RESULTS: Eight healthyvolunteers were given a single dose of alcohol (vodka; 0.6 g of ethanol/kg of body weight) together with a fat load (0.7 g of fat/kg of body weight) in an experimental breakfast or together with dinner 12 h before the experimental breakfast. In comparison to control experiment, alcohol given with breakfast induced increased and prolonged postprandial response of triglyceride-rich lipoproteins (TRL; d < 1.006 g/ml). At the same time TG accumulated also in intermediate density lipoprotein

Název v anglickém jazyce

Postprandial triglyceridemia after single dose of alcohol in healthy young men

Popis výsledku anglicky

BACKGROUND AND AIMS: Moderate alcohol consumption provides protection against cardiovascular disease primarily due to increase of HDL-cholesterol. However, it also has some adverse effects on metabolism of triglycerides (TG). Therefore, we addressed thequestion how a single dose of alcohol affects postprandial lipemia and activities of two enzymes playing a critical role in regulation of triglyceridemia, lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL). METHODS AND RESULTS: Eight healthyvolunteers were given a single dose of alcohol (vodka; 0.6 g of ethanol/kg of body weight) together with a fat load (0.7 g of fat/kg of body weight) in an experimental breakfast or together with dinner 12 h before the experimental breakfast. In comparison to control experiment, alcohol given with breakfast induced increased and prolonged postprandial response of triglyceride-rich lipoproteins (TRL; d < 1.006 g/ml). At the same time TG accumulated also in intermediate density lipoprotein

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nutrition, metabolism, and cardiovascular diseases

ISSN

0939-4753

e-ISSN

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Svazek periodika

23

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

183-188

Kód UT WoS článku

000316762100005

EID výsledku v databázi Scopus

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