Early exercise training after renal transplantation and asymmetric dimethylarginine: the effect of obesity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059066" target="_blank" >RIV/00023001:_____/14:00059066 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/14:A1501CDU RIV/00216208:11120/14:43909227 RIV/00216208:11510/14:10272361

Výsledek na webu

<a href="http://www.karger.com/Article/Pdf/355806" target="_blank" >http://www.karger.com/Article/Pdf/355806</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000355806" target="_blank" >10.1159/000355806</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Early exercise training after renal transplantation and asymmetric dimethylarginine: the effect of obesity

Popis výsledku v původním jazyce

Background/Aims : To assess, in a prospective cohort study of 238 renal transplant patients, our hypothesis that elevated ADMA levels may be influenced by physical exercise and obesity. Methods : Blood samples before and after six months were obtained from 116 transplant patients participating in an aerobic exercise (Group I). A control group consisted of 122 matched transplant patients who did not exercise regularly (Group II). Results : There were no significant differences in ADMA levels between bothgroups before the training program (Group IB vs Group IIB). After six months of exercise, ADMA levels in Group I decreased (Group IB vs Group IA : 3.50 +- 0.45 vs 2.11 +- 0.35mýmol/L; p< 0.01) and were lower compared to those in Group II (Group IA vs Group IIA : 2 11 +- 0 23 vs 3 25 +- 0 34mýmol/L; p< 0 01) Analysis of our results in obese renal transplant recipients (BMI B 30 kg/m(2)) confirmed a smaller effect of exercise training (Group IBO vs Group IAO : 3 75 +- 0 52 vs 3 45 +- 0 45

Název v anglickém jazyce

Early exercise training after renal transplantation and asymmetric dimethylarginine: the effect of obesity

Popis výsledku anglicky

Background/Aims : To assess, in a prospective cohort study of 238 renal transplant patients, our hypothesis that elevated ADMA levels may be influenced by physical exercise and obesity. Methods : Blood samples before and after six months were obtained from 116 transplant patients participating in an aerobic exercise (Group I). A control group consisted of 122 matched transplant patients who did not exercise regularly (Group II). Results : There were no significant differences in ADMA levels between bothgroups before the training program (Group IB vs Group IIB). After six months of exercise, ADMA levels in Group I decreased (Group IB vs Group IA : 3.50 +- 0.45 vs 2.11 +- 0.35mýmol/L; p< 0.01) and were lower compared to those in Group II (Group IA vs Group IIA : 2 11 +- 0 23 vs 3 25 +- 0 34mýmol/L; p< 0 01) Analysis of our results in obese renal transplant recipients (BMI B 30 kg/m(2)) confirmed a smaller effect of exercise training (Group IBO vs Group IAO : 3 75 +- 0 52 vs 3 45 +- 0 45

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FJ - Chirurgie včetně transplantologie

OECD FORD obor

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Projekt

<a href="/cs/project/NT13139" target="_blank" >NT13139: Časná pohybová intervence a selektivní nutrice po transplantaci ledviny: cirkulující endoteliální progenitorové buňky, genový polymorfismus a kardiovaskulární riziko</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Kidney and Blood Pressure Research

ISSN

1420-4096

e-ISSN

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Svazek periodika

39

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

11

Strana od-do

289-298

Kód UT WoS článku

000345093700008

EID výsledku v databázi Scopus

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