Muscle and fat metabolism in obesity after kidney transplantation: No effect of peritoneal dialysis or hemodialysis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11553" target="_blank" >RIV/00216208:11110/12:11553 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/12:43899239 RIV/00023001:_____/12:00056102 RIV/00064165:_____/12:11553 RIV/00023728:_____/12:#0004141

Výsledek na webu

<a href="http://dx.doi.org/10.1053/j.jrn.2011.10.016" target="_blank" >http://dx.doi.org/10.1053/j.jrn.2011.10.016</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Muscle and fat metabolism in obesity after kidney transplantation: No effect of peritoneal dialysis or hemodialysis

Popis výsledku v původním jazyce

Our prospective study analyzed selected adipocytokines: adiponectin (ADPN), leptin, visfatin, and asymmetric dimethylarginine (ADMA) in the plasma of renal transplant recipients previously treated by peritoneal dialysis and hemodialysis. A total of 70 patients were on follow-up for 12 months after transplantation. Of these, 30 patients (group I) developed obesity, and 40 patients were nonobese (group II). All were receiving standard immunosuppressive therapy (cyclosporine A or tacrolimus and mycophenolate mofetil, with prednisone added in the early posttransplant period) and did not differ statistically in HLA typing, age, sex, duration of previous dialysis, history of cardiovascular disease, and rate of rejection episodes. At the end of the study period, there were significant differences between groups I and II (t test, analysis of variance) in plasma: ADPN, 22.30 +/- 10.2 versus 14.3 +/- 7.2 mu g/mL; visfatin, 1.7 +/- 0.1 versus 1.2 +/- 0.1 ng/mL; ADMA, 3.60 +/- 0.47 versus 2.10 +/-

Název v anglickém jazyce

Muscle and fat metabolism in obesity after kidney transplantation: No effect of peritoneal dialysis or hemodialysis

Popis výsledku anglicky

Our prospective study analyzed selected adipocytokines: adiponectin (ADPN), leptin, visfatin, and asymmetric dimethylarginine (ADMA) in the plasma of renal transplant recipients previously treated by peritoneal dialysis and hemodialysis. A total of 70 patients were on follow-up for 12 months after transplantation. Of these, 30 patients (group I) developed obesity, and 40 patients were nonobese (group II). All were receiving standard immunosuppressive therapy (cyclosporine A or tacrolimus and mycophenolate mofetil, with prednisone added in the early posttransplant period) and did not differ statistically in HLA typing, age, sex, duration of previous dialysis, history of cardiovascular disease, and rate of rejection episodes. At the end of the study period, there were significant differences between groups I and II (t test, analysis of variance) in plasma: ADPN, 22.30 +/- 10.2 versus 14.3 +/- 7.2 mu g/mL; visfatin, 1.7 +/- 0.1 versus 1.2 +/- 0.1 ng/mL; ADMA, 3.60 +/- 0.47 versus 2.10 +/-

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

<a href="/cs/project/NS10529" target="_blank" >NS10529: Časná a dlouhodobá funkce transplantované ledviny: vliv peritoneální dialýzy</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Renal Nutrition

ISSN

1051-2276

e-ISSN

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Svazek periodika

22

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

166-170

Kód UT WoS článku

000298638800032

EID výsledku v databázi Scopus

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