In vitro evaluation of ice-cold saline irrigation during catheter radiofrequeny ablation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059136" target="_blank" >RIV/00023001:_____/14:00059136 - isvavai.cz</a>

Výsledek na webu

<a href="http://onlinelibrary.wiley.com/doi/10.1111/jce.12479/pdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/jce.12479/pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jce.12479" target="_blank" >10.1111/jce.12479</a>

Jazyk výsledku

angličtina

Název v původním jazyce

In vitro evaluation of ice-cold saline irrigation during catheter radiofrequeny ablation

Popis výsledku v původním jazyce

IntroductionIrrigated radiofrequency (RF) catheters allow tissue-electrode interface cooling, decreasing thrombus risk while enabling higher RF power delivery. The impact of irrigation with ice-cold saline (ICS) instead of conventional ambient-temperature saline (ATS) on lesion formation is unknown. Methods and ResultsWe performed 120 RF ablations in vitro on porcine left ventricles, using ICS (<5 degrees C) or ATS (21 degrees C) irrigation. For ICS irrigation, the irrigation circuit was cooled externally to maintain delivery of cooled saline at the catheter's tip. We applied 20g of contact force, and delivered 20 W (irrigation 8 or 17 mL/min) or 30 W (irrigation 17 or 30 mL/min) RF power. Temperatures at tissue-electrode interface and 3-mm depth wereassessed by fluoroptic probes. Lesion dimensions were assessed. ICS irrigation cooled the tissue-electrode interface better than ATS (53.9 9.6 degrees C vs. 63 +/- 11.4 degrees C, P < 0.001). Temperatures at 3-mm depth were similar at 30

Název v anglickém jazyce

In vitro evaluation of ice-cold saline irrigation during catheter radiofrequeny ablation

Popis výsledku anglicky

IntroductionIrrigated radiofrequency (RF) catheters allow tissue-electrode interface cooling, decreasing thrombus risk while enabling higher RF power delivery. The impact of irrigation with ice-cold saline (ICS) instead of conventional ambient-temperature saline (ATS) on lesion formation is unknown. Methods and ResultsWe performed 120 RF ablations in vitro on porcine left ventricles, using ICS (<5 degrees C) or ATS (21 degrees C) irrigation. For ICS irrigation, the irrigation circuit was cooled externally to maintain delivery of cooled saline at the catheter's tip. We applied 20g of contact force, and delivered 20 W (irrigation 8 or 17 mL/min) or 30 W (irrigation 17 or 30 mL/min) RF power. Temperatures at tissue-electrode interface and 3-mm depth wereassessed by fluoroptic probes. Lesion dimensions were assessed. ICS irrigation cooled the tissue-electrode interface better than ATS (53.9 9.6 degrees C vs. 63 +/- 11.4 degrees C, P < 0.001). Temperatures at 3-mm depth were similar at 30

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of cardiovascular electrophysiology

ISSN

1045-3873

e-ISSN

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Svazek periodika

25

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

1125-1132

Kód UT WoS článku

000343807600015

EID výsledku v databázi Scopus

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