Geometric ring annuloplasty for aortic valve repair during aortic aneurysm surgery two-year clinical trial results

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F18%3A00077434" target="_blank" >RIV/00023001:_____/18:00077434 - isvavai.cz</a>

Výsledek na webu

<a href="https://journals.lww.com/innovjournal/Fulltext/2018/07000/Geometric_Ring_Annuloplasty_for_Aortic_Valve.3.aspx" target="_blank" >https://journals.lww.com/innovjournal/Fulltext/2018/07000/Geometric_Ring_Annuloplasty_for_Aortic_Valve.3.aspx</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/IMI.0000000000000539" target="_blank" >10.1097/IMI.0000000000000539</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Geometric ring annuloplasty for aortic valve repair during aortic aneurysm surgery two-year clinical trial results

Popis výsledku v původním jazyce

Objective: An aortic annuloplasty ring could be useful for aortic valve repair. This trial evaluated intermediate-term outcomes of internal geometric ring annuloplasty for repair of trileaflet and bicuspid aortic insufficiency associated with ascending aortic and/or aortic root aneurysms. Methods: Under regulatory supervision, 47 patients with aortic insufficiency and ascending aortic (n = 22) and/or aortic root (n = 25) aneurysms were managed with aortic valve repair and aneurysm resection. Valve repair was performed using trileaflet (n = 40) or bicuspid (n = 7) internal geometric rings, together with leaflet reconstruction. Ascending aortic and/or remodeling root replacements were accomplished with Dacron grafts 5 to 7 mm larger than the rings. An Echo Core Lab provided independent echocardiographic assessments, and changes over time were evaluated by Friedman tests. Results: Mean +/- SD age was 60 +/- 14 years, 57% (27/47) were male, 15% (7/47) had bicuspid valves, 87% (41/47) had moderate-to-severe aortic insufficiency, and 13% (6/47) had mild aortic insufficiency. All patients had annular dilatation, with a mean +/- SD of 26.5 +/- 2.6 mm before repair, and mean +/- SD ring sizes were 21.7 +/- 1.7 mm. Follow-up was 42 months (mean = 27 months). No operative mortality or valve-related complications occurred. Two patients died beyond 1 year from nonvalve-related causes. One patient required valve replacement for repair failure. Survival free of complications or valve replacement was 94% at 2 years. Significant reduction in aortic insufficiency and New York Heart Association class were observed (P &lt; 0.0001), and valve gradients remained low. No heart block or direct ring complications occurred. Conclusions: In preliminary regulatory studies, aortic ring annuloplasty seemed safe and effective during aortic aneurysm surgery. This approach could help standardize aortic valve repair.

Název v anglickém jazyce

Geometric ring annuloplasty for aortic valve repair during aortic aneurysm surgery two-year clinical trial results

Popis výsledku anglicky

Objective: An aortic annuloplasty ring could be useful for aortic valve repair. This trial evaluated intermediate-term outcomes of internal geometric ring annuloplasty for repair of trileaflet and bicuspid aortic insufficiency associated with ascending aortic and/or aortic root aneurysms. Methods: Under regulatory supervision, 47 patients with aortic insufficiency and ascending aortic (n = 22) and/or aortic root (n = 25) aneurysms were managed with aortic valve repair and aneurysm resection. Valve repair was performed using trileaflet (n = 40) or bicuspid (n = 7) internal geometric rings, together with leaflet reconstruction. Ascending aortic and/or remodeling root replacements were accomplished with Dacron grafts 5 to 7 mm larger than the rings. An Echo Core Lab provided independent echocardiographic assessments, and changes over time were evaluated by Friedman tests. Results: Mean +/- SD age was 60 +/- 14 years, 57% (27/47) were male, 15% (7/47) had bicuspid valves, 87% (41/47) had moderate-to-severe aortic insufficiency, and 13% (6/47) had mild aortic insufficiency. All patients had annular dilatation, with a mean +/- SD of 26.5 +/- 2.6 mm before repair, and mean +/- SD ring sizes were 21.7 +/- 1.7 mm. Follow-up was 42 months (mean = 27 months). No operative mortality or valve-related complications occurred. Two patients died beyond 1 year from nonvalve-related causes. One patient required valve replacement for repair failure. Survival free of complications or valve replacement was 94% at 2 years. Significant reduction in aortic insufficiency and New York Heart Association class were observed (P &lt; 0.0001), and valve gradients remained low. No heart block or direct ring complications occurred. Conclusions: In preliminary regulatory studies, aortic ring annuloplasty seemed safe and effective during aortic aneurysm surgery. This approach could help standardize aortic valve repair.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Innovations : technology and techniques in cardiothoracic and vascular surgery

ISSN

1556-9845

e-ISSN

—

Svazek periodika

13

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

248-253

Kód UT WoS článku

000445908900003

EID výsledku v databázi Scopus

2-s2.0-85059796422