A rare association of sarcoidosis and severe mitral stenosis in young female

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F18%3A00077466" target="_blank" >RIV/00023001:_____/18:00077466 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.minervamedica.it/en/journals/gazzetta-medica-italiana/article.php?cod=R22Y2018N05A0243" target="_blank" >https://www.minervamedica.it/en/journals/gazzetta-medica-italiana/article.php?cod=R22Y2018N05A0243</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23736/S0393-3660.17.03544-6" target="_blank" >10.23736/S0393-3660.17.03544-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A rare association of sarcoidosis and severe mitral stenosis in young female

Popis výsledku v původním jazyce

Association of sarcoidosis and severe heart valve stenosis is extremely rare entity. We describe the case of a 35-year-old female who presented with coincidence of symptomatic pulmonary sarcoidosis and rapid progression of mitral valve stenosis. During four months of corticostemid therapy her pulmonary sarcoidosis resolved but she developed severe mitral stenosis leading to acute heart failure. She was treated by a semi-urgent surgical mitral valve replacement with St. Jude Medical Masters HP valve prosthesis. There was a massive thrombotic mass on the atrial site of both mitral valve leaflets. Histology analysis of the excised mitral valve specimen was negative for noncaseating granuloma but advanced degenerative changes and myocardial fibrosis were identified. Our patient made a good recovery and currently is asymptomatic on Coumadin, corticosteroid and immunosuppressive medication. Clearly five months of corticosteroid therapy influenced the myocardial histology finding together with the resolution of pulmonary sarcoidosis on her chest X-ray prior to surgery. We are convinced that the rapid mitral valve disease progression was directly associated with sarcoidosis.

Název v anglickém jazyce

A rare association of sarcoidosis and severe mitral stenosis in young female

Popis výsledku anglicky

Association of sarcoidosis and severe heart valve stenosis is extremely rare entity. We describe the case of a 35-year-old female who presented with coincidence of symptomatic pulmonary sarcoidosis and rapid progression of mitral valve stenosis. During four months of corticostemid therapy her pulmonary sarcoidosis resolved but she developed severe mitral stenosis leading to acute heart failure. She was treated by a semi-urgent surgical mitral valve replacement with St. Jude Medical Masters HP valve prosthesis. There was a massive thrombotic mass on the atrial site of both mitral valve leaflets. Histology analysis of the excised mitral valve specimen was negative for noncaseating granuloma but advanced degenerative changes and myocardial fibrosis were identified. Our patient made a good recovery and currently is asymptomatic on Coumadin, corticosteroid and immunosuppressive medication. Clearly five months of corticosteroid therapy influenced the myocardial histology finding together with the resolution of pulmonary sarcoidosis on her chest X-ray prior to surgery. We are convinced that the rapid mitral valve disease progression was directly associated with sarcoidosis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Gazzetta Medica Italiana Archivio per le Scienze Mediche

ISSN

0393-3660

e-ISSN

—

Svazek periodika

177

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

3

Strana od-do

243-245

Kód UT WoS článku

000445247200011

EID výsledku v databázi Scopus

2-s2.0-85046901311