Predictors of physical capacity 6 months after implantation of a full magnetically levitated left ventricular assist device: an analysis from the ELEVATE registry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F20%3A00079916" target="_blank" >RIV/00023001:_____/20:00079916 - isvavai.cz</a>

Výsledek na webu

<a href="https://reader.elsevier.com/reader/sd/pii/S1071916419306505?token=8E10DF735509623C0D48FE1F4F41F4E1C19BBB5FCCFF2E299B82D91D26FBD2F8423D8DB6BED6FC999FD71F92862CF3EE" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S1071916419306505?token=8E10DF735509623C0D48FE1F4F41F4E1C19BBB5FCCFF2E299B82D91D26FBD2F8423D8DB6BED6FC999FD71F92862CF3EE</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cardfail.2020.04.004" target="_blank" >10.1016/j.cardfail.2020.04.004</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Predictors of physical capacity 6 months after implantation of a full magnetically levitated left ventricular assist device: an analysis from the ELEVATE registry

Popis výsledku v původním jazyce

Background: In patients with a continuous-flow left ventricular assist device, preimplant predictors of poor physical performance are not well-described. We aimed to identify predictors of inability to walk more than 300 m on 6-minute walk test (6MWT) 6 months after HeartMate 3 implantation. Methods and Results: Using data from the European Registry of Patients Implanted With a Full Magnetically Levitated LVAD, patients with available 6MWT at 6 months after implantation were included (N = 194) and grouped according to 6MWT distance (6MWD) of &gt;300 m (n = 150) or 6MWD of &lt;300 m (n = 44). Patients walking &lt;300 m were older (60 +/- 10 vs 52 +/- 12 years; P &lt;.001), more often New York Heart Association functional class IV (63% vs 42%; P =.03), and more often had type 2 diabetes (43% vs 17%; P &lt;.001) at implantation. Atrial fibrillation was seen in 57% in those with a 6MWT of &lt;300 m vs 31% in those walking longer (P &lt;.002). Further, hemoglobin and estimated glomerular filtration rate was lower in those walking &lt; 300 m (both P &lt;.01). In multivariable regression analysis, independent predictors of a 6MWD of &lt;300 m were: atrial fibrillation (odds ratio [OR], 3.22; 95% confidence interval [CI], 1.12-8.67), older age (OR for 10-year increment, 2.81; 95% CI, 1.55-5.07), New York Heart Association functional class IV (OR, 3.37; 95% CI, 1.27-8.98), and Interagency Registry for Mechanically Assisted Circulatory Support profile 1 or 2 (OR, 6.53; 95% CI, 1.92-22.19). Conclusions: Six months after HeartMate 3 implantation, 77% of patients walked &gt;300 meters in 6 minutes. Apart from age and measures of heart failure severity, atrial fibrillation at implantation is an independent predictor of low 6MWD at 6 months after implantation.

Název v anglickém jazyce

Predictors of physical capacity 6 months after implantation of a full magnetically levitated left ventricular assist device: an analysis from the ELEVATE registry

Popis výsledku anglicky

Background: In patients with a continuous-flow left ventricular assist device, preimplant predictors of poor physical performance are not well-described. We aimed to identify predictors of inability to walk more than 300 m on 6-minute walk test (6MWT) 6 months after HeartMate 3 implantation. Methods and Results: Using data from the European Registry of Patients Implanted With a Full Magnetically Levitated LVAD, patients with available 6MWT at 6 months after implantation were included (N = 194) and grouped according to 6MWT distance (6MWD) of &gt;300 m (n = 150) or 6MWD of &lt;300 m (n = 44). Patients walking &lt;300 m were older (60 +/- 10 vs 52 +/- 12 years; P &lt;.001), more often New York Heart Association functional class IV (63% vs 42%; P =.03), and more often had type 2 diabetes (43% vs 17%; P &lt;.001) at implantation. Atrial fibrillation was seen in 57% in those with a 6MWT of &lt;300 m vs 31% in those walking longer (P &lt;.002). Further, hemoglobin and estimated glomerular filtration rate was lower in those walking &lt; 300 m (both P &lt;.01). In multivariable regression analysis, independent predictors of a 6MWD of &lt;300 m were: atrial fibrillation (odds ratio [OR], 3.22; 95% confidence interval [CI], 1.12-8.67), older age (OR for 10-year increment, 2.81; 95% CI, 1.55-5.07), New York Heart Association functional class IV (OR, 3.37; 95% CI, 1.27-8.98), and Interagency Registry for Mechanically Assisted Circulatory Support profile 1 or 2 (OR, 6.53; 95% CI, 1.92-22.19). Conclusions: Six months after HeartMate 3 implantation, 77% of patients walked &gt;300 meters in 6 minutes. Apart from age and measures of heart failure severity, atrial fibrillation at implantation is an independent predictor of low 6MWD at 6 months after implantation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of cardiac failure

ISSN

1071-9164

e-ISSN

—

Svazek periodika

26

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

580-587

Kód UT WoS článku

000551280100009

EID výsledku v databázi Scopus

2-s2.0-85086370282