Acute pancreatitis in patients after liver transplantation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F22%3A00083554" target="_blank" >RIV/00023001:_____/22:00083554 - isvavai.cz</a>

Výsledek na webu

<a href="https://annalsoftransplantation.com/abstract/full/idArt/938114" target="_blank" >https://annalsoftransplantation.com/abstract/full/idArt/938114</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.12659/AOT.938114" target="_blank" >10.12659/AOT.938114</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Acute pancreatitis in patients after liver transplantation

Popis výsledku v původním jazyce

Background: Acute pancreatitis (AP) is a relatively rare but serious complication that can occur after organ transplantation.Material/Methods: The aim of this study was to evaluate the incidence, potential risk factors, and course of AP in patients follow-ing liver transplantation at a single large-volume transplant center.Results: Out of a total of 1850 transplanted patients, 49 (2.8%) were diagnosed with AP. Of this group, 37 (75.5%) had a mild form of AP and 12 (24.5%) had a severe form of AP. The mortality rate was 10% overall and 42% in the group of patients with severe AP. An early form of AP (&lt;30 days from transplantation) occurred in 13 patients (26.5%), most of whom presented with severe AP (10 patients, 76.9%); 4 patients died (40%). A late form of AP was diagnosed in 36 patients (73.5%), most of whom had mild AP (34 patients, 94.4%); 1 of 2 patients with severe AP died. The most common AP etiologies were post-ERCP (38.8%), idiopathic (34.7%), and postopera-tive (18.4%). Chronic HBV infection was a risk factor for development of AP (P=0.01).Conclusions: AP in liver transplant recipients was more frequent and more severe than in the general population. This un -favorable course was associated with the occurrence of AP in the early post-transplant period. Liver transplan-tation due to complications of HBV infection was a risk factor for the development of AP.

Název v anglickém jazyce

Acute pancreatitis in patients after liver transplantation

Popis výsledku anglicky

Background: Acute pancreatitis (AP) is a relatively rare but serious complication that can occur after organ transplantation.Material/Methods: The aim of this study was to evaluate the incidence, potential risk factors, and course of AP in patients follow-ing liver transplantation at a single large-volume transplant center.Results: Out of a total of 1850 transplanted patients, 49 (2.8%) were diagnosed with AP. Of this group, 37 (75.5%) had a mild form of AP and 12 (24.5%) had a severe form of AP. The mortality rate was 10% overall and 42% in the group of patients with severe AP. An early form of AP (&lt;30 days from transplantation) occurred in 13 patients (26.5%), most of whom presented with severe AP (10 patients, 76.9%); 4 patients died (40%). A late form of AP was diagnosed in 36 patients (73.5%), most of whom had mild AP (34 patients, 94.4%); 1 of 2 patients with severe AP died. The most common AP etiologies were post-ERCP (38.8%), idiopathic (34.7%), and postopera-tive (18.4%). Chronic HBV infection was a risk factor for development of AP (P=0.01).Conclusions: AP in liver transplant recipients was more frequent and more severe than in the general population. This un -favorable course was associated with the occurrence of AP in the early post-transplant period. Liver transplan-tation due to complications of HBV infection was a risk factor for the development of AP.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30219 - Gastroenterology and hepatology

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Annals of transplantation

ISSN

1425-9524

e-ISSN

2329-0358

Svazek periodika

27

Číslo periodika v rámci svazku

16 December

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

"art. no. e938114"

Kód UT WoS článku

000911669900001

EID výsledku v databázi Scopus

2-s2.0-85144179030