Impact of routine extracorporeal cardiopulmonary resuscitation service on the availability of donor organs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F25%3A00085687" target="_blank" >RIV/00023001:_____/25:00085687 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21730/25:00390753 RIV/00216208:11110/25:10486245 RIV/00064203:_____/25:10486245 RIV/00064165:_____/25:10486245

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S105324982401862X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S105324982401862X?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.healun.2024.09.009" target="_blank" >10.1016/j.healun.2024.09.009</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of routine extracorporeal cardiopulmonary resuscitation service on the availability of donor organs

Popis výsledku v původním jazyce

BACKGROUND: In refractory cardiac arrest, extracorporeal cardiopulmonary resuscitation may increase the survival chance. However, in cases of unsuccessful treatment, extracorporeal cardiopulmonary resuscitation may additionally provide an important source of organ donors. Therefore, we hypothesized that implementing extracorporeal cardiopulmonary resuscitation service into a highvolume cardiac arrest center&apos;s routine would increases organ donors&apos; availability. METHODS: Our retrospective observational study analyzed out-of-hospital cardiac arrest patients admitted to the General University Hospital in Prague between 2007 and 2020. The following groups were analyzed regarding the recruitment of donors: before and after extracorporeal cardiopulmonary resuscitation implementation. We assessed the number of donors referred, the number of organs harvested, and the organ&apos;s survival. RESULTS: We analyzed the results of 1,158 patients after out-of-hospital cardiac arrest. In the conventional approach period, 11 donors were referred, of which 7 were accepted. During the extracorporeal cardiopulmonary resuscitation period, the number of donors increased to 80, of whom 42 were accepted. The number of donated organs was 18 and 119 in the respective periods, corresponding to 3.6 vs 13.2 (p = 0.033) harvested organs per year. One-year survival of transplanted organs was 94.4% vs 99.2%, and 5-year survival was 94.4% vs 95.9% in relevant periods. Conventional and extracorporeal cardiopulmonary resuscitation did not affect donor organ survival. CONCLUSION: Establishing a high-volume cardiac arrest center providing an extracorporeal cardio-pulmonary resuscitation service may increase not only the number of prolonged cardiac arrest survi-vors but also the number of organ donors. In addition, the performances of donated organs were high and comparable between both treatment methods. J Heart Lung Transplant 2025;44:872-879 (c) Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation.

Název v anglickém jazyce

Impact of routine extracorporeal cardiopulmonary resuscitation service on the availability of donor organs

Popis výsledku anglicky

BACKGROUND: In refractory cardiac arrest, extracorporeal cardiopulmonary resuscitation may increase the survival chance. However, in cases of unsuccessful treatment, extracorporeal cardiopulmonary resuscitation may additionally provide an important source of organ donors. Therefore, we hypothesized that implementing extracorporeal cardiopulmonary resuscitation service into a highvolume cardiac arrest center&apos;s routine would increases organ donors&apos; availability. METHODS: Our retrospective observational study analyzed out-of-hospital cardiac arrest patients admitted to the General University Hospital in Prague between 2007 and 2020. The following groups were analyzed regarding the recruitment of donors: before and after extracorporeal cardiopulmonary resuscitation implementation. We assessed the number of donors referred, the number of organs harvested, and the organ&apos;s survival. RESULTS: We analyzed the results of 1,158 patients after out-of-hospital cardiac arrest. In the conventional approach period, 11 donors were referred, of which 7 were accepted. During the extracorporeal cardiopulmonary resuscitation period, the number of donors increased to 80, of whom 42 were accepted. The number of donated organs was 18 and 119 in the respective periods, corresponding to 3.6 vs 13.2 (p = 0.033) harvested organs per year. One-year survival of transplanted organs was 94.4% vs 99.2%, and 5-year survival was 94.4% vs 95.9% in relevant periods. Conventional and extracorporeal cardiopulmonary resuscitation did not affect donor organ survival. CONCLUSION: Establishing a high-volume cardiac arrest center providing an extracorporeal cardio-pulmonary resuscitation service may increase not only the number of prolonged cardiac arrest survi-vors but also the number of organ donors. In addition, the performances of donated organs were high and comparable between both treatment methods. J Heart Lung Transplant 2025;44:872-879 (c) Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30213 - Transplantation

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of heart and lung transplantation

ISSN

1053-2498

e-ISSN

1557-3117

Svazek periodika

44

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

872-879

Kód UT WoS článku

001503686500004

EID výsledku v databázi Scopus

2-s2.0-85205377800