The Possible Protective Role of Bilirubin on Oxidative Stress Related Morbidity in Preterm Infants
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F22%3AN0000023" target="_blank" >RIV/00023698:_____/22:N0000023 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11120/22:43922690
Výsledek na webu
<a href="https://www.tandfonline.com/doi/abs/10.1080/15513815.2021.2008069" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/15513815.2021.2008069</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/15513815.2021.2008069" target="_blank" >10.1080/15513815.2021.2008069</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The Possible Protective Role of Bilirubin on Oxidative Stress Related Morbidity in Preterm Infants
Popis výsledku v původním jazyce
Aims: To evaluate the effect of bilirubin levels in the first week of life on the frequency of oxidative-stress related morbidity. Methods: We included all preterm infants with a gestational age less than 32 weeks. The mean total serum bilirubin of the first week of life was measured and compared between infants with and without oxidative stress related morbidity. Results: A total of 116 preterm infants were included. Univariate analysis showed that mean ± SD TSB levels were statistically significantly lower in infants with chronic lung disease (95 ± 31.4micromole/l vs 119 ± 31micromole/l, p = 0.019), necrotizing enterocolitis (94.4 ± 29micromole/l vs 118 ± 31micromole/l p = 0.044) and patent ductus arteriosus (104 ± 33micromole/l vs 120 ± 30micromole/l p = 0.018). However, when adjusted for gestational age, there were no longer statistically significant differences observed. Conclusion: Elevated bilirubin levels in the first week of life are not protective against the oxidative stress related morbidity in very preterm infants. © 2021 Taylor & Francis Group, LLC.
Název v anglickém jazyce
The Possible Protective Role of Bilirubin on Oxidative Stress Related Morbidity in Preterm Infants
Popis výsledku anglicky
Aims: To evaluate the effect of bilirubin levels in the first week of life on the frequency of oxidative-stress related morbidity. Methods: We included all preterm infants with a gestational age less than 32 weeks. The mean total serum bilirubin of the first week of life was measured and compared between infants with and without oxidative stress related morbidity. Results: A total of 116 preterm infants were included. Univariate analysis showed that mean ± SD TSB levels were statistically significantly lower in infants with chronic lung disease (95 ± 31.4micromole/l vs 119 ± 31micromole/l, p = 0.019), necrotizing enterocolitis (94.4 ± 29micromole/l vs 118 ± 31micromole/l p = 0.044) and patent ductus arteriosus (104 ± 33micromole/l vs 120 ± 30micromole/l p = 0.018). However, when adjusted for gestational age, there were no longer statistically significant differences observed. Conclusion: Elevated bilirubin levels in the first week of life are not protective against the oxidative stress related morbidity in very preterm infants. © 2021 Taylor & Francis Group, LLC.
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
30209 - Paediatrics
Návaznosti výsledku
Projekt
—
Návaznosti
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Fetal and Pediatric Pathology
ISSN
1551-3815
e-ISSN
1551-3823
Svazek periodika
41
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
5
Strana od-do
904-908
Kód UT WoS článku
—
EID výsledku v databázi Scopus
2-s2.0-85120826311