White matter hyperintensities - from medical comorbidities to bipolar disorders and back

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F11%3A00001179" target="_blank" >RIV/00023752:_____/11:00001179 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/11:43906705

Výsledek na webu

<a href="http://informahealthcare.com/doi/abs/10.3109/07853890.2011.595733" target="_blank" >http://informahealthcare.com/doi/abs/10.3109/07853890.2011.595733</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3109/07853890.2011.595733" target="_blank" >10.3109/07853890.2011.595733</a>

Jazyk výsledku

angličtina

Název v původním jazyce

White matter hyperintensities - from medical comorbidities to bipolar disorders and back

Popis výsledku v původním jazyce

White matter hyperintensities (WMHs) are among the most replicated neuroimaging findings in studies of patients with bipolar disorders (BD). Despite the high rates of WMHs, their role and etiology in BD are not well understood. WMHs occur in multiple other conditions frequently co-morbid with BD. From the available studies it seems that WMHs are not a primary risk factor/endophenotype for BD. More likely, these lesions indicate the presence of medical co-morbidities with specific links to BD. Furthermore, the etiology of the WMHs in BD may represent different processes depending on age. In certain forms of BD, such as pediatric BD, WMHs may represent co-morbidity with developmental disorders. High frequency of migraine in BD and high prevalence of WMHsin migraine may suggest that a substantial proportion of WMHs in early adulthood to midlife BD subjects may be related to co-morbidity with migraine. Among elderly subjects with BD, or those with late-onset BD, WMHs are likely related to

Název v anglickém jazyce

White matter hyperintensities - from medical comorbidities to bipolar disorders and back

Popis výsledku anglicky

White matter hyperintensities (WMHs) are among the most replicated neuroimaging findings in studies of patients with bipolar disorders (BD). Despite the high rates of WMHs, their role and etiology in BD are not well understood. WMHs occur in multiple other conditions frequently co-morbid with BD. From the available studies it seems that WMHs are not a primary risk factor/endophenotype for BD. More likely, these lesions indicate the presence of medical co-morbidities with specific links to BD. Furthermore, the etiology of the WMHs in BD may represent different processes depending on age. In certain forms of BD, such as pediatric BD, WMHs may represent co-morbidity with developmental disorders. High frequency of migraine in BD and high prevalence of WMHsin migraine may suggest that a substantial proportion of WMHs in early adulthood to midlife BD subjects may be related to co-morbidity with migraine. Among elderly subjects with BD, or those with late-onset BD, WMHs are likely related to

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

—

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Annals of Medicine

ISSN

0785-3890

e-ISSN

—

Svazek periodika

43

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

NO - Norské království

Počet stran výsledku

10

Strana od-do

571-580

Kód UT WoS článku

000296638000001

EID výsledku v databázi Scopus

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