EEG coherence in a mental arithmetic task performance in first episode schizophrenia and schizoaffective disorder

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F18%3A43919472" target="_blank" >RIV/00023752:_____/18:43919472 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/18:43917129

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1388245718312148" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1388245718312148</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.clinph.2018.08.020" target="_blank" >10.1016/j.clinph.2018.08.020</a>

Jazyk výsledku

angličtina

Název v původním jazyce

EEG coherence in a mental arithmetic task performance in first episode schizophrenia and schizoaffective disorder

Popis výsledku v původním jazyce

Objectives: To evaluate the coherence values of the cortical bands in patients with first episode schizophrenia and schizoaffective disorder during the performance of a mental arithmetic task. Method: We analysed EEG coherence in the resting state and subsequently while counting down from 200 in steps of 7 in 32 first episode schizophrenia patients (SZ), 32 patients with first episode schizoaffective disorder (SA) and 40 healthy controls (HC). Results: Task performance in HC is characterised by decreased coherence in the alpha bands and increased coherence in the beta 2 and gamma bands in frontal sites. In SZ, coherence decreases in the alpha band, whereas in SA it substantially increases in the alpha, beta1, beta 2 and gamma bands. Conclusions: Despite no differences in performance on a behavioural level, SA patients demonstrate a paradoxical increase in both low and fast frequency bands during the performance of a mental arithmetic task, while, patients with SZ show a decreased coherence in the alpha band, presumably alluding to the excessive excitatory (in SA) and inhibitory (in SZ) mechanisms in cognitive processing. Significance: The current study provides evidence for the distinction of neurophysiological mechanisms of cognitive processing between SZ and SA.

Název v anglickém jazyce

EEG coherence in a mental arithmetic task performance in first episode schizophrenia and schizoaffective disorder

Popis výsledku anglicky

Objectives: To evaluate the coherence values of the cortical bands in patients with first episode schizophrenia and schizoaffective disorder during the performance of a mental arithmetic task. Method: We analysed EEG coherence in the resting state and subsequently while counting down from 200 in steps of 7 in 32 first episode schizophrenia patients (SZ), 32 patients with first episode schizoaffective disorder (SA) and 40 healthy controls (HC). Results: Task performance in HC is characterised by decreased coherence in the alpha bands and increased coherence in the beta 2 and gamma bands in frontal sites. In SZ, coherence decreases in the alpha band, whereas in SA it substantially increases in the alpha, beta1, beta 2 and gamma bands. Conclusions: Despite no differences in performance on a behavioural level, SA patients demonstrate a paradoxical increase in both low and fast frequency bands during the performance of a mental arithmetic task, while, patients with SZ show a decreased coherence in the alpha band, presumably alluding to the excessive excitatory (in SA) and inhibitory (in SZ) mechanisms in cognitive processing. Significance: The current study provides evidence for the distinction of neurophysiological mechanisms of cognitive processing between SZ and SA.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Neurophysiology

ISSN

1388-2457

e-ISSN

—

Svazek periodika

129

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

10

Strana od-do

2315-2324

Kód UT WoS článku

000447765400013

EID výsledku v databázi Scopus

2-s2.0-85053395347