Anisotropic Conductivity of Rat Head Phantom and its Influence on Electroencephalogram Source Localization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F22%3A43920816" target="_blank" >RIV/00023752:_____/22:43920816 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26220/22:PU144207

Výsledek na webu

<a href="https://ieeexplore.ieee.org/document/9684466" target="_blank" >https://ieeexplore.ieee.org/document/9684466</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/ACCESS.2022.3143952" target="_blank" >10.1109/ACCESS.2022.3143952</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Anisotropic Conductivity of Rat Head Phantom and its Influence on Electroencephalogram Source Localization

Popis výsledku v původním jazyce

In this paper we deal with a simplified anisotropic rat head phantom development and the investigation of the influence of the anisotropic white matter on electroencephalogram source localization. The proposed phantom is based on the cubic cross cell composition combined with agar mixture to set desired electrical conductivity anisotropic ratio. For the fabrication of the phantom, the 3D printed technology is exploited. Starting from a real rat brain, we proposed a simplified brain model incorporating the actual dimensions, shape and conductivity parameters of both grey and white matter containing simultaneously relevant deep-brain electrical signal sources. Five testing dipoles were located in the areas corresponding to the active brain regions. A single dipole localization error was calculated by comparing an inverse solution with a dipole position obtained from a computer tomography image. Neglecting anisotropy had a rather weak effect on localization error of a single testing dipole in our model. The reliability map was computed and interpreted in terms of spatial similarity between distributed inverse solutions involving isotropic and anisotropic forward models. We found spatially specific error increases located close to the electrodes and in the vicinity of anisotropic compartment. Hence, areas to be most sensitive to neglecting anisotropy in our model were identified.

Název v anglickém jazyce

Anisotropic Conductivity of Rat Head Phantom and its Influence on Electroencephalogram Source Localization

Popis výsledku anglicky

In this paper we deal with a simplified anisotropic rat head phantom development and the investigation of the influence of the anisotropic white matter on electroencephalogram source localization. The proposed phantom is based on the cubic cross cell composition combined with agar mixture to set desired electrical conductivity anisotropic ratio. For the fabrication of the phantom, the 3D printed technology is exploited. Starting from a real rat brain, we proposed a simplified brain model incorporating the actual dimensions, shape and conductivity parameters of both grey and white matter containing simultaneously relevant deep-brain electrical signal sources. Five testing dipoles were located in the areas corresponding to the active brain regions. A single dipole localization error was calculated by comparing an inverse solution with a dipole position obtained from a computer tomography image. Neglecting anisotropy had a rather weak effect on localization error of a single testing dipole in our model. The reliability map was computed and interpreted in terms of spatial similarity between distributed inverse solutions involving isotropic and anisotropic forward models. We found spatially specific error increases located close to the electrodes and in the vicinity of anisotropic compartment. Hence, areas to be most sensitive to neglecting anisotropy in our model were identified.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30405 - Medical biotechnology related ethics

Projekt

<a href="/cs/project/GA18-16218S" target="_blank" >GA18-16218S: Elektromagnetické modely zvířecích mozků</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

IEEE Access

ISSN

2169-3536

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

21497519

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

12

Strana od-do

9877-9888

Kód UT WoS článku

000826170800001

EID výsledku v databázi Scopus

2-s2.0-85123386449