Společnost vstřícná životu s demencí (dementia-friendly community) a její implikace ve zdravotnictví

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F23%3A43921234" target="_blank" >RIV/00023752:_____/23:43921234 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/23:10466556 RIV/00216208:11120/23:43925937

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0920996423003122?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0920996423003122?via%3Dihub</a>

DOI - Digital Object Identifier

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Jazyk výsledku

čeština

Název v původním jazyce

Společnost vstřícná životu s demencí (dementia-friendly community) a její implikace ve zdravotnictví

Popis výsledku v původním jazyce

Principal goal of the article is to inform health care professionals about the concept of dementia-friendly community (DFC) reflecting the contemporary thinking of living with dementia, i.e. dementia as a disability, equal human rights, a sense of meaning. Experiences from abroad and from the Czechia are discussed with special attention to implementation of this concept in the health care facilities. The National Action Plan for Alzheimer´s Disease 2020-2030 (NAPAN) is presented, which shows that the Czech Government, ministries, specialists, care providers, informal careers and even the people with dementia worked together on the improvement in this field. The purpose of this paper is to bring the principles of DFC closer to the physicians and other health care professionals and support friendly and helpful approach to people living with dementia when providing health care to them. The multidisciplinary cooperation of GPs, geriatricians, neurologists, psychiatrists etc. is emphasized. An example of a regional project in Middle Bohemia is presented looking for criteria and ways of evaluation of the effect of DFC.

Název v anglickém jazyce

The dementia-friendly community and its implications for healthcare

Popis výsledku anglicky

Objectives: To compare the prevalence, regulations, and pharmacovigilance practices of clozapine use in Eastern European countries (except Russia).Methods: Questionnaires and data from administrative databases (2016 and 2021), package inserts and national guidelines were collected from 21 co-authors from 21 countries. Reports of clozapine adverse drug reactions (ADRs) sent to the global pharmacovigilance database (VigiBase™) were analyzed from introduction to December 31, 2022.Results: Clozapine prescription among antipsychotics in 2021 varied six-fold across countries, from 2.8 % in the Czech Republic to 15.8 % in Montenegro. The utilization of antipsychotics in both 2016 and 2021 was highest in Croatia, and lowest in Serbia in 2016, and Montenegro in 2021, which had half the defined daily dose (DDD)/1000/day compared to the Croatian data. From 2016 to 2021, the prevalence of antipsychotic use increased in almost all countries; the proportion of clozapine use mainly remained unchanged. Differences were detected in hematological monitoring requirements and clozapine approved indications. Only a few national schizophrenia guidelines mention clozapine-induced myocarditis or individual titration schemes. The VigiBase search indicated major underreporting regarding clozapine and its fatal outcomes. By comparison, the United Kingdom had less than half the population of these Eastern European countries but reported to VigiBase more clozapine ADRs by 89-fold and clozapine fatal outcomes by almost 300-fold.Conclusion: Clozapine is under-utilized in Eastern European countries. Introducing individualized clozapine treatment schedules may help to maximize clozapine benefits and safety. Major improvement is needed in reporting clozapine ADRs and fatal outcomes in Eastern European countries.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

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OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Časopis lékařů českých

ISSN

0008-7335

e-ISSN

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Svazek periodika

162

Číslo periodika v rámci svazku

2-3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

67-75

Kód UT WoS článku

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EID výsledku v databázi Scopus

2-s2.0-85168869077