Challenges in defining treatment-resistant mania in adults: A systematic review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F24%3A43921213" target="_blank" >RIV/00023752:_____/24:43921213 - isvavai.cz</a>

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/10.1111/bdi.13383" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/bdi.13383</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/bdi.13383" target="_blank" >10.1111/bdi.13383</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Challenges in defining treatment-resistant mania in adults: A systematic review

Popis výsledku v původním jazyce

Objectives: To review the definitions of treatment-resistant mania (TRM) in the literature and propose criteria for an operationalized definition. Methods: A systematic search of five databases (MEDLINE, EMBASE, PsychInfo, Cochrane Central, and CINAHL) and data extraction of eligible articles. Results: In total, 47 articles addressing the concept of TRM were included, comprising 16 case reports, 11 case series, 3 randomized clinical trials, 8 open-label clinical trials, 1 experimental study, 7 narrative reviews, and 1 systematic review. While reviews discussed several challenges in defining TRM, definitions varied substantially based on different criteria for severity of mania, duration of mania, and use of specific therapeutic agents with minimal dosages and duration of treatment. Only a handful of the reviewed articles operationalized these criteria. Conclusion: While the concept of TRM has been discussed in the literature for over three decades, we could not find an agreed-upon operationalized definition based on specific criteria. We propose and discuss a possible definition that could be used by clinicians to guide their practice and by researchers to assess the prevalence of TRM and develop and test interventions targeting TRM.

Název v anglickém jazyce

Challenges in defining treatment-resistant mania in adults: A systematic review

Popis výsledku anglicky

Objectives: To review the definitions of treatment-resistant mania (TRM) in the literature and propose criteria for an operationalized definition. Methods: A systematic search of five databases (MEDLINE, EMBASE, PsychInfo, Cochrane Central, and CINAHL) and data extraction of eligible articles. Results: In total, 47 articles addressing the concept of TRM were included, comprising 16 case reports, 11 case series, 3 randomized clinical trials, 8 open-label clinical trials, 1 experimental study, 7 narrative reviews, and 1 systematic review. While reviews discussed several challenges in defining TRM, definitions varied substantially based on different criteria for severity of mania, duration of mania, and use of specific therapeutic agents with minimal dosages and duration of treatment. Only a handful of the reviewed articles operationalized these criteria. Conclusion: While the concept of TRM has been discussed in the literature for over three decades, we could not find an agreed-upon operationalized definition based on specific criteria. We propose and discuss a possible definition that could be used by clinicians to guide their practice and by researchers to assess the prevalence of TRM and develop and test interventions targeting TRM.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bipolar Disorders

ISSN

1398-5647

e-ISSN

1399-5618

Svazek periodika

26

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

DK - Dánské království

Počet stran výsledku

15

Strana od-do

7-21

Kód UT WoS článku

001101186900001

EID výsledku v databázi Scopus

2-s2.0-85176937689