Physical Health of Patients with Schizophrenia. Management of Antipsychotic-Induced Side Effects and Treatment of Comorbid Somatic Conditions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F24%3A43921391" target="_blank" >RIV/00023752:_____/24:43921391 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.cambridge.org/core/books/abs/mental-health-research-and-practice/physical-health-of-patients-with-schizophrenia/D5514BEC02234D4EF5E528170C42D7C8" target="_blank" >https://www.cambridge.org/core/books/abs/mental-health-research-and-practice/physical-health-of-patients-with-schizophrenia/D5514BEC02234D4EF5E528170C42D7C8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/9781009067287.014" target="_blank" >10.1017/9781009067287.014</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Physical Health of Patients with Schizophrenia. Management of Antipsychotic-Induced Side Effects and Treatment of Comorbid Somatic Conditions

Popis výsledku v původním jazyce

Schizophrenia is associated with increased risk of somatic comorbities and reduced life expectancy [1]. At the same time, available data suggests that continuous antipsychotic treatment decreases the mortality rate of schizophrenia patients [2,3]. Since both short- and long-term administration of antipsychotics induce numerous physical side effects, it is important that low – or the minimum effective – doses are used [4]. Patients diagnosed with schizophrenia and treated with antipsychotics frequently also suffer from psychiatric (e.g., depression, anxiety, insomnia) and somatic (e.g., cardiovascular diseases, infections, metabolic disorders) comorbidities. While often underreported and undertreated, somatic comorbidities represent a severe burden for schizophrenia patients [5]. In a Hungarian nationwide register-based study, researchers showed that patients with schizophrenia (n = 65,169) had a statistically significantly higher all-cause mortality rate than control participants (risk ratio = 2,4; P &lt; 0.0001) [1]. The most prevalent comorbidities in this study were cerebro- and cardiovascular diseases (53.7%), followed by acute lower respiratory infections and other infections [1].

Název v anglickém jazyce

Physical Health of Patients with Schizophrenia. Management of Antipsychotic-Induced Side Effects and Treatment of Comorbid Somatic Conditions

Popis výsledku anglicky

Schizophrenia is associated with increased risk of somatic comorbities and reduced life expectancy [1]. At the same time, available data suggests that continuous antipsychotic treatment decreases the mortality rate of schizophrenia patients [2,3]. Since both short- and long-term administration of antipsychotics induce numerous physical side effects, it is important that low – or the minimum effective – doses are used [4]. Patients diagnosed with schizophrenia and treated with antipsychotics frequently also suffer from psychiatric (e.g., depression, anxiety, insomnia) and somatic (e.g., cardiovascular diseases, infections, metabolic disorders) comorbidities. While often underreported and undertreated, somatic comorbidities represent a severe burden for schizophrenia patients [5]. In a Hungarian nationwide register-based study, researchers showed that patients with schizophrenia (n = 65,169) had a statistically significantly higher all-cause mortality rate than control participants (risk ratio = 2,4; P &lt; 0.0001) [1]. The most prevalent comorbidities in this study were cerebro- and cardiovascular diseases (53.7%), followed by acute lower respiratory infections and other infections [1].

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Mental Health Research and Practice

ISBN

978-1-00-906728-7

Počet stran výsledku

18

Strana od-do

210-227

Počet stran knihy

404

Název nakladatele

Cambridge University Press

Místo vydání

New York, Cambridge

Kód UT WoS kapitoly

—