Bisphenol A Release from Dental Composites and Resin-Modified Glass Ionomers under Two Polymerization Conditions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F22%3AN0000011" target="_blank" >RIV/00023761:_____/22:N0000011 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22330/22:43925488 RIV/00064165:_____/22:10435425 RIV/00216208:11110/22:10435425

Výsledek na webu

<a href="https://www.mdpi.com/2073-4360/14/1/46" target="_blank" >https://www.mdpi.com/2073-4360/14/1/46</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/polym14010046" target="_blank" >10.3390/polym14010046</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Bisphenol A Release from Dental Composites and Resin-Modified Glass Ionomers under Two Polymerization Conditions

Popis výsledku v původním jazyce

Bisphenol A (BPA)-based monomers are commonly contained in dental resin-based materials. As BPA is an endocrine disruptor, its long-term release from restorative composites and resin-modified glass ionomers (RM-GICs) under two polymerization conditions was measured in this study. Specimens of two conventional composites containing BPA-based monomers, two "BPA-free" composites, and two RM-GICs were polymerized from one side for 20 s at 1300 mW/cm(2) or for 5 s at 3000 mW/cm(2). The amounts of BPA released in artificial saliva and methanol after 1, 4, 9, 16, 35, 65, 130, and 260 days were measured using liquid chromatography-tandem mass spectrometry. The highest amounts of BPA were released from conventional composites, followed by RM-GICs, while the least was released from "BPA-free" composites. Amounts of released BPA were significantly higher in methanol and decreased gradually after the first day. Fast polymerization (5 s at 3000 mW/cm(2)) resulted in a significantly higher release of BPA after 1 day, but the effect of polymerization conditions was not significant overall. In conclusion, fast polymerization increased the initial release of BPA, but the released amounts were significantly lower than the current tolerable daily intake (4 mu g/kg body weight/day) even in methanol, representing the worst-case scenario of BPA release.

Název v anglickém jazyce

Bisphenol A Release from Dental Composites and Resin-Modified Glass Ionomers under Two Polymerization Conditions

Popis výsledku anglicky

Bisphenol A (BPA)-based monomers are commonly contained in dental resin-based materials. As BPA is an endocrine disruptor, its long-term release from restorative composites and resin-modified glass ionomers (RM-GICs) under two polymerization conditions was measured in this study. Specimens of two conventional composites containing BPA-based monomers, two "BPA-free" composites, and two RM-GICs were polymerized from one side for 20 s at 1300 mW/cm(2) or for 5 s at 3000 mW/cm(2). The amounts of BPA released in artificial saliva and methanol after 1, 4, 9, 16, 35, 65, 130, and 260 days were measured using liquid chromatography-tandem mass spectrometry. The highest amounts of BPA were released from conventional composites, followed by RM-GICs, while the least was released from "BPA-free" composites. Amounts of released BPA were significantly higher in methanol and decreased gradually after the first day. Fast polymerization (5 s at 3000 mW/cm(2)) resulted in a significantly higher release of BPA after 1 day, but the effect of polymerization conditions was not significant overall. In conclusion, fast polymerization increased the initial release of BPA, but the released amounts were significantly lower than the current tolerable daily intake (4 mu g/kg body weight/day) even in methanol, representing the worst-case scenario of BPA release.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polymers

ISSN

2073-4360

e-ISSN

2073-4360

Svazek periodika

14

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

14

Strana od-do

Article Number 46

Kód UT WoS článku

000751393000001

EID výsledku v databázi Scopus

2-s2.0-85121826475