Release of Bisphenol A from Milled and 3D-Printed Dental Polycarbonate Materials

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F21%3AN0000030" target="_blank" >RIV/00023761:_____/21:N0000030 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/21:10433220 RIV/00064165:_____/21:10433220

Výsledek na webu

<a href="https://www.mdpi.com/1996-1944/14/19/5868/htm" target="_blank" >https://www.mdpi.com/1996-1944/14/19/5868/htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ma14195868" target="_blank" >10.3390/ma14195868</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Release of Bisphenol A from Milled and 3D-Printed Dental Polycarbonate Materials

Popis výsledku v původním jazyce

Polycarbonates are polymers of bisphenol A (BPA), a well-known endocrine disruptor. This study evaluated the release of BPA from polycarbonate crowns that were (1) milled from Temp Premium Flexible (ZPF, Zirkonzahn, Italy) or Tizian Blank Polycarbonate (TBP, Schutz Dental, Germany), or (2) 3D-printed (Makrolon 2805, Covestro, Germany). Commercial prefabricated polycarbonate crowns (3M, USA) and milled poly(methyl methacrylate) (PMMA) crowns (Temp Basic, Zirkonzahn, Italy) were included for comparison. The crowns were stored at 37 & DEG;C in artificial saliva (AS) or methanol, which represented the worst-case scenario of BPA release. Extracts were collected after 1 day, 1 week, 1 month and 3 months. BPA concentrations were measured using liquid chromatography-tandem mass spectrometry. The amounts of released BPA were expressed in micrograms per gram of material (mu g/g). After 1 day, the highest amounts of BPA were measured from milled polycarbonates, TBP (methanol: 32.2 & PLUSMN; 3.8 mu g/g, AS: 7.1 & PLUSMN; 0.9 mu g/g) and ZPF (methanol 22.8 & PLUSMN; 7.7 mu g/g, AS: 0.3 & PLUSMN; 0.03 mu g/g), followed by 3D-printed crowns (methanol: 11.1 & PLUSMN; 2.3 mu g/g, AS: 0.1 & PLUSMN; 0.1 mu g/g) and prefabricated crowns (methanol: 8.0 & PLUSMN; 1.6 mu g/g, AS: 0.07 & PLUSMN; 0.02 mu g/g). Between 1 week and 3 months, the average daily release of BPA in methanol and AS decreased below 2 mu g/g and 0.6 mu g/g, respectively. No BPA was released from PMMA in AS, and the cumulative amount released in methanol was 0.2 & PLUSMN; 0.06 mu g/g. In conclusion, polycarbonates could be a relevant source of BPA, but the current tolerable daily intake of BPA (4 mu g/kg body weight) should not be exceeded.

Název v anglickém jazyce

Release of Bisphenol A from Milled and 3D-Printed Dental Polycarbonate Materials

Popis výsledku anglicky

Polycarbonates are polymers of bisphenol A (BPA), a well-known endocrine disruptor. This study evaluated the release of BPA from polycarbonate crowns that were (1) milled from Temp Premium Flexible (ZPF, Zirkonzahn, Italy) or Tizian Blank Polycarbonate (TBP, Schutz Dental, Germany), or (2) 3D-printed (Makrolon 2805, Covestro, Germany). Commercial prefabricated polycarbonate crowns (3M, USA) and milled poly(methyl methacrylate) (PMMA) crowns (Temp Basic, Zirkonzahn, Italy) were included for comparison. The crowns were stored at 37 & DEG;C in artificial saliva (AS) or methanol, which represented the worst-case scenario of BPA release. Extracts were collected after 1 day, 1 week, 1 month and 3 months. BPA concentrations were measured using liquid chromatography-tandem mass spectrometry. The amounts of released BPA were expressed in micrograms per gram of material (mu g/g). After 1 day, the highest amounts of BPA were measured from milled polycarbonates, TBP (methanol: 32.2 & PLUSMN; 3.8 mu g/g, AS: 7.1 & PLUSMN; 0.9 mu g/g) and ZPF (methanol 22.8 & PLUSMN; 7.7 mu g/g, AS: 0.3 & PLUSMN; 0.03 mu g/g), followed by 3D-printed crowns (methanol: 11.1 & PLUSMN; 2.3 mu g/g, AS: 0.1 & PLUSMN; 0.1 mu g/g) and prefabricated crowns (methanol: 8.0 & PLUSMN; 1.6 mu g/g, AS: 0.07 & PLUSMN; 0.02 mu g/g). Between 1 week and 3 months, the average daily release of BPA in methanol and AS decreased below 2 mu g/g and 0.6 mu g/g, respectively. No BPA was released from PMMA in AS, and the cumulative amount released in methanol was 0.2 & PLUSMN; 0.06 mu g/g. In conclusion, polycarbonates could be a relevant source of BPA, but the current tolerable daily intake of BPA (4 mu g/kg body weight) should not be exceeded.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MATERIALS

ISSN

1996-1944

e-ISSN

1996-1944

Svazek periodika

14

Číslo periodika v rámci svazku

19

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

14

Strana od-do

5868

Kód UT WoS článku

000727371100001

EID výsledku v databázi Scopus

2-s2.0-85117022652