Ocular and orbital lesions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F15%3A%230007170" target="_blank" >RIV/00023884:_____/15:#0007170 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Ocular and orbital lesions

Popis výsledku v původním jazyce

Treatment of orbital and ocular lesions using radiosurgery faces a number of technical and dosimetric challenges. Fixation of the orbit is a challenge as is the potential for image distortion given the eccentric location of the target. This location also can impact dose calculations. Stereotactic radiosurgery (SRS) is attractive, however, because of the ability to deliver highly conformal radiation doses with great accuracy. Both Gamma Knife and Linac systems have been used successfully. Uveal melanomas are typically treated with doses between 25 and 45 Gy while attempting to keep the optic nerve dose below 10 Gy. Similarly metastases can be treated using the same techniques. Non-oncologic indications include age-related macular degeneration (ARMD) and glaucoma. Gamma Knife has been shown effective at diminishing subretinal neovascularization in ARMD. The mechanism of action in alleviating pain in glaucoma is not yet understood.

Název v anglickém jazyce

Ocular and orbital lesions

Popis výsledku anglicky

Treatment of orbital and ocular lesions using radiosurgery faces a number of technical and dosimetric challenges. Fixation of the orbit is a challenge as is the potential for image distortion given the eccentric location of the target. This location also can impact dose calculations. Stereotactic radiosurgery (SRS) is attractive, however, because of the ability to deliver highly conformal radiation doses with great accuracy. Both Gamma Knife and Linac systems have been used successfully. Uveal melanomas are typically treated with doses between 25 and 45 Gy while attempting to keep the optic nerve dose below 10 Gy. Similarly metastases can be treated using the same techniques. Non-oncologic indications include age-related macular degeneration (ARMD) and glaucoma. Gamma Knife has been shown effective at diminishing subretinal neovascularization in ARMD. The mechanism of action in alleviating pain in glaucoma is not yet understood.

Druh

C - Kapitola v odborné knize

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Principles and Practice of Stereotactic Radiosurgery

ISBN

978-1-4614-8363-2

Počet stran výsledku

22

Strana od-do

743-764

Počet stran knihy

842

Název nakladatele

Springer New York

Místo vydání

New York

Kód UT WoS kapitoly

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