Operations of adults with congenital heart disease - Single center experience with 10 years results

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F16%3A%230006603" target="_blank" >RIV/00023884:_____/16:#0006603 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Operations of adults with congenital heart disease - Single center experience with 10 years results

Popis výsledku v původním jazyce

During the last 10 years, 844 operations of 805 adults with congenital heart disease (CHD)were performed in Hospital Na Homolce in Prague, Czech Republic. The median age was 37(interquartile range 25 49, full range 16 81) years. Operations of complex and rare CHD represented 47%. Forty-four percent of patients (354) underwent previous cardiac surgery in childhood or adulthood. Three and more operations were performed in 14% (113 patients). Combined surgical procedures were performed in 70% of operations. Thirty-day mortality was 1.36%, hospital mortality 1.7% and 5-year survival probability 97%. The risk factors for early and late mortality were NYHA class III and IV symptoms(p < 0.0001; OR 30.8), history of heart failure (p = 0.001; OR 6.7), cyanosis ( p < 0.0001; OR 60.5), number of previous operations (p = 0.00033), presence of mechanical prosthetic valves(p = 0.0032; OR 3.7) and univentricular circulation (p = 0.0276; OR 5.4). The difference was not significant for arrhythmias (p = 0.078), pulmonary hypertension (p = 0.072), age at operation(p = 0.372) and gender (p = 0.48). Centralization of adult CHD care in a high volume center carries very good surgical results with low early and late mortality. It is important to perform the operations in time and to eliminate all residual lesions by combined surgical procedure. The presence of pediatric cardiac surgeon is necessary for the operations of complex CHD.

Název v anglickém jazyce

Operations of adults with congenital heart disease - Single center experience with 10 years results

Popis výsledku anglicky

During the last 10 years, 844 operations of 805 adults with congenital heart disease (CHD)were performed in Hospital Na Homolce in Prague, Czech Republic. The median age was 37(interquartile range 25 49, full range 16 81) years. Operations of complex and rare CHD represented 47%. Forty-four percent of patients (354) underwent previous cardiac surgery in childhood or adulthood. Three and more operations were performed in 14% (113 patients). Combined surgical procedures were performed in 70% of operations. Thirty-day mortality was 1.36%, hospital mortality 1.7% and 5-year survival probability 97%. The risk factors for early and late mortality were NYHA class III and IV symptoms(p < 0.0001; OR 30.8), history of heart failure (p = 0.001; OR 6.7), cyanosis ( p < 0.0001; OR 60.5), number of previous operations (p = 0.00033), presence of mechanical prosthetic valves(p = 0.0032; OR 3.7) and univentricular circulation (p = 0.0276; OR 5.4). The difference was not significant for arrhythmias (p = 0.078), pulmonary hypertension (p = 0.072), age at operation(p = 0.372) and gender (p = 0.48). Centralization of adult CHD care in a high volume center carries very good surgical results with low early and late mortality. It is important to perform the operations in time and to eliminate all residual lesions by combined surgical procedure. The presence of pediatric cardiac surgeon is necessary for the operations of complex CHD.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cor et Vasa

ISSN

0010-8650

e-ISSN

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Svazek periodika

58

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

10

Strana od-do

"e317"-"e327"

Kód UT WoS článku

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EID výsledku v databázi Scopus

2-s2.0-84955595098