Comparison of the Convolution algorithm with TMR10 for Leksell Gamma knife and dosimetric verification with radiochromic gel dosimeter

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F18%3A00007316" target="_blank" >RIV/00023884:_____/18:00007316 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00177016:_____/17:N0000048 RIV/68407700:21340/18:00326316 RIV/00064203:_____/18:10375331

Výsledek na webu

<a href="http://dx.doi.org/10.1002/acm2.12238" target="_blank" >http://dx.doi.org/10.1002/acm2.12238</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/acm2.12238" target="_blank" >10.1002/acm2.12238</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of the Convolution algorithm with TMR10 for Leksell Gamma knife and dosimetric verification with radiochromic gel dosimeter

Popis výsledku v původním jazyce

The Convolution algorithm, implemented in Leksell GammaPlan (R) ver. Here, 10, is the first algorithm for Leksell Gamma Knife that takes heterogeneities into account and models dose build-up effects close to tissue boundaries. The aim of this study was preliminary comparison of the Convolution and TMR10 algorithms for real clinical cases and dosimetric verification of the algorithms, using measurements in a phantom. A total of 25 patients involved in comparison of the Convolution and TMR10 algorithms were divided into three groups: patients with benign tumors close to heterogeneities, patients with functional disorders, and patients with tumors located far from heterogeneities. Differences were observed especially in the group of patients with tumors close to heterogeneities, where the difference in maximal dose to critical structures for the Convolution algorithm was up to 15% compared to the TMR10 algorithm. Dosimetric verification of the algorithm was performed, using a radiochromic gel dosimeter based on Turnbull blue dye in a special heterogeneous phantom. Relative dose distributions measured with the radiochromic gel dosimeter agreed very well with both the TMR10 and Convolution calculations. We observed small discrepancies in the direction in which the largest inhomogeneity was positioned. Verification results indicated that the Convolution algorithm provides a different dose distribution, especially in regions close to heterogeneities and particularly for lower isodose volumes. However, the results obtained with gamma analyses in the gel dosimetry experiment did not verify the assumption that the Convolution algorithm provides more accurate dose calculation.

Název v anglickém jazyce

Comparison of the Convolution algorithm with TMR10 for Leksell Gamma knife and dosimetric verification with radiochromic gel dosimeter

Popis výsledku anglicky

The Convolution algorithm, implemented in Leksell GammaPlan (R) ver. Here, 10, is the first algorithm for Leksell Gamma Knife that takes heterogeneities into account and models dose build-up effects close to tissue boundaries. The aim of this study was preliminary comparison of the Convolution and TMR10 algorithms for real clinical cases and dosimetric verification of the algorithms, using measurements in a phantom. A total of 25 patients involved in comparison of the Convolution and TMR10 algorithms were divided into three groups: patients with benign tumors close to heterogeneities, patients with functional disorders, and patients with tumors located far from heterogeneities. Differences were observed especially in the group of patients with tumors close to heterogeneities, where the difference in maximal dose to critical structures for the Convolution algorithm was up to 15% compared to the TMR10 algorithm. Dosimetric verification of the algorithm was performed, using a radiochromic gel dosimeter based on Turnbull blue dye in a special heterogeneous phantom. Relative dose distributions measured with the radiochromic gel dosimeter agreed very well with both the TMR10 and Convolution calculations. We observed small discrepancies in the direction in which the largest inhomogeneity was positioned. Verification results indicated that the Convolution algorithm provides a different dose distribution, especially in regions close to heterogeneities and particularly for lower isodose volumes. However, the results obtained with gamma analyses in the gel dosimetry experiment did not verify the assumption that the Convolution algorithm provides more accurate dose calculation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Clinical Medical Physics

ISSN

1526-9914

e-ISSN

—

Svazek periodika

19

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

138-144

Kód UT WoS článku

000427481300016

EID výsledku v databázi Scopus

2-s2.0-85038071618