Fetal Dose Evaluation for Pregnant Patients on Leksell Gamma Knife Perfexion/Icon

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F24%3A00009624" target="_blank" >RIV/00023884:_____/24:00009624 - isvavai.cz</a>

Výsledek na webu

<a href="https://karger.com/sfn/article-abstract/102/2/65/893970/Fetal-Dose-Evaluation-for-Pregnant-Patients-on?redirectedFrom=fulltext" target="_blank" >https://karger.com/sfn/article-abstract/102/2/65/893970/Fetal-Dose-Evaluation-for-Pregnant-Patients-on?redirectedFrom=fulltext</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000535366" target="_blank" >10.1159/000535366</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fetal Dose Evaluation for Pregnant Patients on Leksell Gamma Knife Perfexion/Icon

Popis výsledku v původním jazyce

It is a normal procedure to avoid the application of ionizing radiation during pregnancy. In very rare occasions treatment can be performed but doses to the fetus must be evaluated and reported and the patient must sign informed consent. There can occur two types of damage caused by ionizing radiation – deterministic and stochastic effects. Deterministic effects may occur after reaching a certain threshold (100 mGy for this study), meanwhile, stochastic effects have no limit and their probability rises with dose. This study focuses on deterministic effects. This study compares the dose measured on phantom for the area of the pelvis and the dose measured on 3 patients with dosimeters positioned on the pelvis irradiated on Leksell Gamma Knife Perfexion/Icon. The mean dose for measurement on phantom for pelvis was 0.73 ± 0.76 mGy and for patients, it was 1.28 mGy, 0.493 mGy, 0.549 mGy which is 80 times lower, 200 times lower, 180 times lower than the threshold for deterministic effects, respectively. The measurement carried on phantom served as the base for drafting informed consent and provided initial proof that treatment can be safely delivered. Measurements performed on patients only confirmed that irradiation of pregnant patients on Leksell Gamma Knife Perfexion/Icon is safe relative to the deterministic effects. Nevertheless, pregnant patients should be treated with ionizing radiation only in very extraordinary situations.

Název v anglickém jazyce

Fetal Dose Evaluation for Pregnant Patients on Leksell Gamma Knife Perfexion/Icon

Popis výsledku anglicky

It is a normal procedure to avoid the application of ionizing radiation during pregnancy. In very rare occasions treatment can be performed but doses to the fetus must be evaluated and reported and the patient must sign informed consent. There can occur two types of damage caused by ionizing radiation – deterministic and stochastic effects. Deterministic effects may occur after reaching a certain threshold (100 mGy for this study), meanwhile, stochastic effects have no limit and their probability rises with dose. This study focuses on deterministic effects. This study compares the dose measured on phantom for the area of the pelvis and the dose measured on 3 patients with dosimeters positioned on the pelvis irradiated on Leksell Gamma Knife Perfexion/Icon. The mean dose for measurement on phantom for pelvis was 0.73 ± 0.76 mGy and for patients, it was 1.28 mGy, 0.493 mGy, 0.549 mGy which is 80 times lower, 200 times lower, 180 times lower than the threshold for deterministic effects, respectively. The measurement carried on phantom served as the base for drafting informed consent and provided initial proof that treatment can be safely delivered. Measurements performed on patients only confirmed that irradiation of pregnant patients on Leksell Gamma Knife Perfexion/Icon is safe relative to the deterministic effects. Nevertheless, pregnant patients should be treated with ionizing radiation only in very extraordinary situations.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Stereotactic and Functional Neurosurgery

ISSN

1011-6125

e-ISSN

—

Svazek periodika

102

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

9

Strana od-do

65-73

Kód UT WoS článku

001164053200001

EID výsledku v databázi Scopus

2-s2.0-85182552454