Synergized mixtures of Apiaceae essential oils and related plant-borne compounds: Larvicidal effectiveness on the filariasis vector Culex quinquefasciatus Say

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F17%3A00003768" target="_blank" >RIV/00027006:_____/17:00003768 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.indcrop.2016.11.059" target="_blank" >http://dx.doi.org/10.1016/j.indcrop.2016.11.059</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.indcrop.2016.11.059" target="_blank" >10.1016/j.indcrop.2016.11.059</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Synergized mixtures of Apiaceae essential oils and related plant-borne compounds: Larvicidal effectiveness on the filariasis vector Culex quinquefasciatus Say

Popis výsledku v původním jazyce

The recent outbreaks of mosquito-borne diseases, such as chikungunya and Zika virus, highlighted the pivotal importance of effective mosquito control programs. Nowadays, Culicidae management is being challenging, due to the rapid development of resistance to synthetic pesticides and the spread of highly invasive mosquito vectors worldwide. This research explored the chemical composition of four Apiaceae essential oils (EOs) from Trachyspermum ammi, Smyrnium olusatrum, Pimpinella anisum and Helosciadium nodiflorum and their potential as sources of synergistic binary mixtures with high effectiveness against larvae of the filariasis vector Culex quinquefasciatus. The essential oils were all highly toxic to the larvae, showing LC50 of 17.6, 17.5, 25.9 and 20.6 µl L-1, respectively. GC–MS analysis put in evidence thymol, (E)-anethole, myristicin and (Z)-ß-ocimene, and isofuranodiene and germacrone as the main essential oil components, respectively. Three effective EOs were selected to prepare binary mixtures. T. ammi + P. anisum (ratio 1:2) and S. olusatrum + P. anisum (ratio 1:1) were the most toxic larvicidal blends, showing LC50 of 15.2 and 16.9, µl L-1, respectively. LT50 values were 45 and 30 min, respectively. Notably, short time exposure to both binary mixtures strongly reduced emergence rates, fertility and natality of C. quinquefasciatus that survived after the treatment at the larval stage. Larvicidal assays assessing the acute toxicity of EO main constituents, i.e. germacrone, isofuranodiene and (E)-anethole, were carried out. LC50 were 18.6 mg L-1, 33.7 mg L-1 and 24.8 µl L-1. Overall, our results pointed out the promising potential of these EOs to develop cheap and effective mosquito larvicides, as well as the importance to consider the synergistic effects among the tested botanicals during the design of novel mosquito larvicides.

Název v anglickém jazyce

Synergized mixtures of Apiaceae essential oils and related plant-borne compounds: Larvicidal effectiveness on the filariasis vector Culex quinquefasciatus Say

Popis výsledku anglicky

The recent outbreaks of mosquito-borne diseases, such as chikungunya and Zika virus, highlighted the pivotal importance of effective mosquito control programs. Nowadays, Culicidae management is being challenging, due to the rapid development of resistance to synthetic pesticides and the spread of highly invasive mosquito vectors worldwide. This research explored the chemical composition of four Apiaceae essential oils (EOs) from Trachyspermum ammi, Smyrnium olusatrum, Pimpinella anisum and Helosciadium nodiflorum and their potential as sources of synergistic binary mixtures with high effectiveness against larvae of the filariasis vector Culex quinquefasciatus. The essential oils were all highly toxic to the larvae, showing LC50 of 17.6, 17.5, 25.9 and 20.6 µl L-1, respectively. GC–MS analysis put in evidence thymol, (E)-anethole, myristicin and (Z)-ß-ocimene, and isofuranodiene and germacrone as the main essential oil components, respectively. Three effective EOs were selected to prepare binary mixtures. T. ammi + P. anisum (ratio 1:2) and S. olusatrum + P. anisum (ratio 1:1) were the most toxic larvicidal blends, showing LC50 of 15.2 and 16.9, µl L-1, respectively. LT50 values were 45 and 30 min, respectively. Notably, short time exposure to both binary mixtures strongly reduced emergence rates, fertility and natality of C. quinquefasciatus that survived after the treatment at the larval stage. Larvicidal assays assessing the acute toxicity of EO main constituents, i.e. germacrone, isofuranodiene and (E)-anethole, were carried out. LC50 were 18.6 mg L-1, 33.7 mg L-1 and 24.8 µl L-1. Overall, our results pointed out the promising potential of these EOs to develop cheap and effective mosquito larvicides, as well as the importance to consider the synergistic effects among the tested botanicals during the design of novel mosquito larvicides.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GF - Choroby, škůdci, plevely a ochrana rostlin

OECD FORD obor

—

Projekt

<a href="/cs/project/QJ1510160" target="_blank" >QJ1510160: Nové technologie získávání biologicky aktivních látek z léčivých a aromatických rostlin jako zdrojů účinných látek botanických pesticidů a potravinových doplňků</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Industrial Crops and Products

ISSN

0926-6690

e-ISSN

—

Svazek periodika

96

Číslo periodika v rámci svazku

February

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

186-195

Kód UT WoS článku

000394556900023

EID výsledku v databázi Scopus

—