Rationale for developing novel mosquito larvicides based on isofuranodiene microemulsions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F19%3A00005394" target="_blank" >RIV/00027006:_____/19:00005394 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41210/19:80952

Výsledek na webu

<a href="https://link.springer.com/content/pdf/10.1007/s10340-018-01076-3" target="_blank" >https://link.springer.com/content/pdf/10.1007/s10340-018-01076-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10340-018-01076-3" target="_blank" >10.1007/s10340-018-01076-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Rationale for developing novel mosquito larvicides based on isofuranodiene microemulsions

Popis výsledku v původním jazyce

Isofuranodiene is a bioactive furanosesquiterpene occurring as the major volatile compound in the essential oil from Smyrnium olusatrum (Apiaceae). It has a notable potentiality to be used as a botanical insecticide. However, its low solubility together with susceptibility to oxidation and thermal degradation limits its application on a wide scale. To face these challenges, isofuranodiene was encapsulated in stable microemulsions (MEs) at two concentrations (ME 750: 0.75%, ME 375: 0.375%). We assessed the larvicidal activity in the short term and after several days of exposure of pure isofuranodiene and its MEs against the filariasis vector Culex quinquefasciatus. The impact of ME-based larvicide at sublethal concentrations on adult emergence was evaluated. Finally, to shed light on potential ecotoxicology risks for nontarget invertebrates, MEs were tested on the aquatic microcrustacean Daphnia magna and on the earthworm Eisenia fetida. Pure isofuranodiene and S. olusatrum leaf essential oil, used as controls, showed their potential as mosquito larvicidal agents (LC50 of 29.2 and 18.6LL(-1), respectively). Isofuranodiene formulated in ME 750 was effective against C. quinquefasciatus larvae, leading to significant larval mortality over time and a marked decrease in adult emergence. Both isofuranodiene MEs showed little impact on the nontarget aquatic microcrustacean Daphnia magna (ME 750 and ME 375: mortality <19% after 48h of exposure at 32mL L-1 and 20mL L-1, respectively) as well as on earthworms (ME 750 and ME 375: no mortality and mortality <7% after 14days of exposure to 1000mgkg(-1), respectively), outlining their potential employ in vector control operations.

Název v anglickém jazyce

Rationale for developing novel mosquito larvicides based on isofuranodiene microemulsions

Popis výsledku anglicky

Isofuranodiene is a bioactive furanosesquiterpene occurring as the major volatile compound in the essential oil from Smyrnium olusatrum (Apiaceae). It has a notable potentiality to be used as a botanical insecticide. However, its low solubility together with susceptibility to oxidation and thermal degradation limits its application on a wide scale. To face these challenges, isofuranodiene was encapsulated in stable microemulsions (MEs) at two concentrations (ME 750: 0.75%, ME 375: 0.375%). We assessed the larvicidal activity in the short term and after several days of exposure of pure isofuranodiene and its MEs against the filariasis vector Culex quinquefasciatus. The impact of ME-based larvicide at sublethal concentrations on adult emergence was evaluated. Finally, to shed light on potential ecotoxicology risks for nontarget invertebrates, MEs were tested on the aquatic microcrustacean Daphnia magna and on the earthworm Eisenia fetida. Pure isofuranodiene and S. olusatrum leaf essential oil, used as controls, showed their potential as mosquito larvicidal agents (LC50 of 29.2 and 18.6LL(-1), respectively). Isofuranodiene formulated in ME 750 was effective against C. quinquefasciatus larvae, leading to significant larval mortality over time and a marked decrease in adult emergence. Both isofuranodiene MEs showed little impact on the nontarget aquatic microcrustacean Daphnia magna (ME 750 and ME 375: mortality <19% after 48h of exposure at 32mL L-1 and 20mL L-1, respectively) as well as on earthworms (ME 750 and ME 375: no mortality and mortality <7% after 14days of exposure to 1000mgkg(-1), respectively), outlining their potential employ in vector control operations.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Pest Science

ISSN

1612-4758

e-ISSN

1612-4766

Svazek periodika

92

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

13

Strana od-do

909-921

Kód UT WoS článku

000463146700045

EID výsledku v databázi Scopus

2-s2.0-85060602826