Nucleolar transplantation and human embryogenesis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F13%3A%230001811" target="_blank" >RIV/00027014:_____/13:#0001811 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.vuzv.cz/sites/File/_privat/13040.pdf" target="_blank" >http://www.vuzv.cz/sites/File/_privat/13040.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-94-007-5818-6_15" target="_blank" >10.1007/978-94-007-5818-6_15</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nucleolar transplantation and human embryogenesis

Popis výsledku v původním jazyce

Fully grown mammalian oocytes as well as very early cleavage stage mammalian embryos contain inactive and atypical nucleoli that arc very distinct from nucleoli in stem or differentiated cells. It has been commonly accepted that these nucleoli serve as astorage site of material(s) from which, as the embryo develops, typical active nucleoli are gradually formed. For this reason, these atypical nucleoli are called the nucleolus precursor bodies (NPBs). It has also been demonstrated that the number and distribution of NPBs in pronuclei in human embryos can serve as a simple noninvasive indicator of further embryonic development. The invention of the enucleolation method as well as some recently published results clearly showed some additional roles of NPHs and clarified their Significance in normal embryonic development. In our chapter, these new results will be discussed especially in the context of their use in human assisted reproduction.

Název v anglickém jazyce

Nucleolar transplantation and human embryogenesis

Popis výsledku anglicky

Fully grown mammalian oocytes as well as very early cleavage stage mammalian embryos contain inactive and atypical nucleoli that arc very distinct from nucleoli in stem or differentiated cells. It has been commonly accepted that these nucleoli serve as astorage site of material(s) from which, as the embryo develops, typical active nucleoli are gradually formed. For this reason, these atypical nucleoli are called the nucleolus precursor bodies (NPBs). It has also been demonstrated that the number and distribution of NPBs in pronuclei in human embryos can serve as a simple noninvasive indicator of further embryonic development. The invention of the enucleolation method as well as some recently published results clearly showed some additional roles of NPHs and clarified their Significance in normal embryonic development. In our chapter, these new results will be discussed especially in the context of their use in human assisted reproduction.

Druh

C - Kapitola v odborné knize

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/GPP302%2F11%2FP069" target="_blank" >GPP302/11/P069: Úloha a funkce jadérka v oogenezi a časném embryonálním vývoji.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Proteins of the Nucleolus: Regulation, Translocation, & Biomedical Functions

ISBN

9400758170

Počet stran výsledku

15

Strana od-do

343-357

Počet stran knihy

377

Název nakladatele

Springer Science+Business Media

Místo vydání

Dordrecht

Kód UT WoS kapitoly

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