Hydrophobically Modified Celluloses: Preparation, Structure and Application

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F13%3A%230001954" target="_blank" >RIV/00027014:_____/13:#0001954 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.vuzv.cz/sites/File/_privat/13183.pdf" target="_blank" >http://www.vuzv.cz/sites/File/_privat/13183.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Hydrophobically Modified Celluloses: Preparation, Structure and Application

Popis výsledku v původním jazyce

Cellulose is the most abundant organic material in the Earth. This polysaccharide has been used for preparing of various derivatives of medicinal importance. Among them, oxidized monocarboxy cellulose (MCC) and/or carboxymethylcellulose (CMC) have many applications including food, pharmacy, medicinal materials, cosmetics etc. Both MCC and CMC contain reactive carboxylic groups and thus may undergo further chemical modifications involving carboxyls to obtain novel perspective derivatives. This work is focused on methyl esterification and following amidation of MCC and CMC with various amidation reagents. Methyl esters were prepared by reaction of mentioned polysaccharides with methanol at acidic conditions. Then obtained methyl esters were used for amino-de-alkoxylation with primary amines, hydrazine and hydroxylamine reagents. Another approach included one-step microwave-assisted amidation of MCC or CMC by the same reagents. Substitution and purity of the reaction products were monitor

Název v anglickém jazyce

Hydrophobically Modified Celluloses: Preparation, Structure and Application

Popis výsledku anglicky

Cellulose is the most abundant organic material in the Earth. This polysaccharide has been used for preparing of various derivatives of medicinal importance. Among them, oxidized monocarboxy cellulose (MCC) and/or carboxymethylcellulose (CMC) have many applications including food, pharmacy, medicinal materials, cosmetics etc. Both MCC and CMC contain reactive carboxylic groups and thus may undergo further chemical modifications involving carboxyls to obtain novel perspective derivatives. This work is focused on methyl esterification and following amidation of MCC and CMC with various amidation reagents. Methyl esters were prepared by reaction of mentioned polysaccharides with methanol at acidic conditions. Then obtained methyl esters were used for amino-de-alkoxylation with primary amines, hydrazine and hydroxylamine reagents. Another approach included one-step microwave-assisted amidation of MCC or CMC by the same reagents. Substitution and purity of the reaction products were monitor

Druh

D - Stať ve sborníku

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP503%2F11%2F2479" target="_blank" >GAP503/11/2479: Inhibice intestinální absorpce sterolů hydrofobně modifikovanými polysacharidy</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the 9th International Conference on Polysaccharides-Glycoscience

ISBN

978-80-86238-58-6

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

53-57

Název nakladatele

Czech Chemical Society, Novotneho Lavka 5, Prague, Czech Republic

Místo vydání

Prague

Místo konání akce

Prague

Datum konání akce

6. 11. 2013

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

000341216900011