Antimicrobial polyhydroxybutyrate submicron fiber mat loaded with extract of Hypericium perforatum

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027022%3A_____%2F22%3AN0000002" target="_blank" >RIV/00027022:_____/22:N0000002 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.kspbtjpb.org/journal/view.html?doi=10.5010/JPB.2022.49.3.257" target="_blank" >http://www.kspbtjpb.org/journal/view.html?doi=10.5010/JPB.2022.49.3.257</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5010/JPB.2022.49.3.257" target="_blank" >10.5010/JPB.2022.49.3.257</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antimicrobial polyhydroxybutyrate submicron fiber mat loaded with extract of Hypericium perforatum

Popis výsledku v původním jazyce

The aim of this work was to prepare a new biodegradable polyhydroxybutyrate (PHB) submicron fiber mat loaded with hypericin-rich Hypericum perforatum raw extract by centrifugal spinning technology, an alternative approach to the traditional method of electrospinning to fabricate nanofibers or microfibers from solutions at high speed and low cost. Hypericins in methanol/acetone extract of H. perforatum were determined by UHPLC-MS/MS and HPLC/PDA. Submicron fiber mats composed of pure PHB or PHB enriched with H. perforatum extract were prepared using a pilot plant demonstrator for the centrifugal spinning technology and characterized by SEM. Singlet oxygen production was quantified by the 1,3-diphenylisobenzofuran (DPIBF) method in hexane. The results proved a significant production of singlet oxygen by the prepared submicron fiber mat. We also found a significant antibacterial activity against the bacterial strain Escherichia coli CCM 5417 by a method in accordance with JIS Z 2801/ISO 22196 standards. The H. perforatum extract-enriched PHB submicron fiber mats showed potential for the development of self-cleaning and antimicrobial air filters.

Název v anglickém jazyce

Antimicrobial polyhydroxybutyrate submicron fiber mat loaded with extract of Hypericium perforatum

Popis výsledku anglicky

The aim of this work was to prepare a new biodegradable polyhydroxybutyrate (PHB) submicron fiber mat loaded with hypericin-rich Hypericum perforatum raw extract by centrifugal spinning technology, an alternative approach to the traditional method of electrospinning to fabricate nanofibers or microfibers from solutions at high speed and low cost. Hypericins in methanol/acetone extract of H. perforatum were determined by UHPLC-MS/MS and HPLC/PDA. Submicron fiber mats composed of pure PHB or PHB enriched with H. perforatum extract were prepared using a pilot plant demonstrator for the centrifugal spinning technology and characterized by SEM. Singlet oxygen production was quantified by the 1,3-diphenylisobenzofuran (DPIBF) method in hexane. The results proved a significant production of singlet oxygen by the prepared submicron fiber mat. We also found a significant antibacterial activity against the bacterial strain Escherichia coli CCM 5417 by a method in accordance with JIS Z 2801/ISO 22196 standards. The H. perforatum extract-enriched PHB submicron fiber mats showed potential for the development of self-cleaning and antimicrobial air filters.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

<a href="/cs/project/TH03020466" target="_blank" >TH03020466: Inovované zařízení a technologie pro průmyslovou výrobu nanovláken vyfukováním z roztoků.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Plant Biotechnology

ISSN

1229-2818

e-ISSN

2384-1397

Svazek periodika

49

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

KR - Korejská republika

Počet stran výsledku

14

Strana od-do

257-270

Kód UT WoS článku

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EID výsledku v databázi Scopus

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