Diagnostický význam sledování protilátkové odpovědi u aktinobacilové pleuropneumonie (App) selat

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Diagnostic relevance of detection of antibody response to Actinobacillus pleuropneumoniae (App) infection in piglets

Popis výsledku v původním jazyce

The results of the study was the characterization of the course of antibody response after infection with App serotype 9 in piglets with different types and levels of antigen-specific immunity and the distinguishing of colostrum-derived antibodies from post-infection antibodies on the basis of their isotype characterization. The titres of serum and bronchoalveolar lavages (BALF) immunoglobulin IgG, IgM and IgA antibodies specific for LPS App9 were determined by isotype-specific indirect enzyme linked immunosorbent assays.In animals, that did not encounter App infection and did not passively ingest antigen-specific antibodies, antibody response was not recorded either in serum or in BALF. Piglets exposed to pathogen produced serum IgM and IgA in BALF, followed by IgG. Based on the assessment of specific IgM antibodies in sera and IgA antibodies in BALF, it is possible to detect subclinically infected animals, even in the presence of colostrum-derived antibodies (IgG).

Název v anglickém jazyce

Diagnostic relevance of detection of antibody response to Actinobacillus pleuropneumoniae (App) infection in piglets

Popis výsledku anglicky

The results of the study was the characterization of the course of antibody response after infection with App serotype 9 in piglets with different types and levels of antigen-specific immunity and the distinguishing of colostrum-derived antibodies from post-infection antibodies on the basis of their isotype characterization. The titres of serum and bronchoalveolar lavages (BALF) immunoglobulin IgG, IgM and IgA antibodies specific for LPS App9 were determined by isotype-specific indirect enzyme linked immunosorbent assays.In animals, that did not encounter App infection and did not passively ingest antigen-specific antibodies, antibody response was not recorded either in serum or in BALF. Piglets exposed to pathogen produced serum IgM and IgA in BALF, followed by IgG. Based on the assessment of specific IgM antibodies in sera and IgA antibodies in BALF, it is possible to detect subclinically infected animals, even in the presence of colostrum-derived antibodies (IgG).

Druh

D - Stať ve sborníku

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

18th International Pig Veterinary Society Congress, June 27 - July 1, 2004, Hamburg

ISBN

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ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

422-422

Název nakladatele

IPVS Veranstaltungs GmbH

Místo vydání

Germany

Místo konání akce

Hamburg, Germany

Datum konání akce

27. 6. 2004

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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