Systémová a lokální protilátková odpověď po experimentální infekci původcem Actinobacillus pleuropneumonia selat s pasivní a aktivní imunitou

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F05%3A06000035" target="_blank" >RIV/00027162:_____/05:06000035 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Systemic and local antibody responses after experimental infection with Actinobacillus pleuropneumoniae in piglets with passive or active immunity

Popis výsledku v původním jazyce

In our study,we described different dynamics of humoral immune responses in serum and bronchoalveolar lavage fluids (BALF) after experimental infection with Actinobacillus pleuropneumoniae (APP) in piglets with different stages of immunity mediated byhigh titers of colostrum-derived APP-specific antibodies and/or a low dose APP infection in the early postnatal period.A typical primary immune response was observed in specific antibody-free piglets infected with a challenge infection. Colostrum-derived immunoglobulin-G (IgG) antibodies persisted in sera and BALF up to the age of 8 weeks.However, they did not prevent induction of specific-primary antibody response. It was demonstr.by the increase of specific IgM antibodies in sera. The infectioninduced anincrease in the levels of IgA antibodies in BALF regardless the severity of infection and presence of specific antibodies.The specific antibodies of IgG isotype increased only in BALF from piglets without colostrum-derived antibodies

Název v anglickém jazyce

Systemic and local antibody responses after experimental infection with Actinobacillus pleuropneumoniae in piglets with passive or active immunity

Popis výsledku anglicky

In our study,we described different dynamics of humoral immune responses in serum and bronchoalveolar lavage fluids (BALF) after experimental infection with Actinobacillus pleuropneumoniae (APP) in piglets with different stages of immunity mediated byhigh titers of colostrum-derived APP-specific antibodies and/or a low dose APP infection in the early postnatal period.A typical primary immune response was observed in specific antibody-free piglets infected with a challenge infection. Colostrum-derived immunoglobulin-G (IgG) antibodies persisted in sera and BALF up to the age of 8 weeks.However, they did not prevent induction of specific-primary antibody response. It was demonstr.by the increase of specific IgM antibodies in sera. The infectioninduced anincrease in the levels of IgA antibodies in BALF regardless the severity of infection and presence of specific antibodies.The specific antibodies of IgG isotype increased only in BALF from piglets without colostrum-derived antibodies

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

<a href="/cs/project/GA524%2F01%2F0290" target="_blank" >GA524/01/0290: Charakteristika imunitní odpovědi respiračního traktu prasat na infekci a imunizaci Actinobacillus pleuropneumoniae</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Veterinary Medicine B

ISSN

0931-1793

e-ISSN

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Svazek periodika

52

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

190-196

Kód UT WoS článku

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EID výsledku v databázi Scopus

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