The effect of bacterial contamination of semen on sperm chromatin integrity and standard semen parameters in men from infertile couples
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F12%3A%230000870" target="_blank" >RIV/00027162:_____/12:#0000870 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1111/j.1439-0272.2011.01198.x" target="_blank" >http://dx.doi.org/10.1111/j.1439-0272.2011.01198.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1439-0272.2011.01198.x" target="_blank" >10.1111/j.1439-0272.2011.01198.x</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The effect of bacterial contamination of semen on sperm chromatin integrity and standard semen parameters in men from infertile couples
Popis výsledku v původním jazyce
A considerable proportion of male factor infertility cases are associated with inflammatory processes. The most common sexually transmissible agents causing sexually transmitted diseases in industrial countries are Chlamydia trachomatis, genital Ureaplasma and Mycoplasma spp. This study was undertaken to investigate whether these bacterial contaminants in semen affect sperm quality parameters and particularly DNA integrity (detected by sperm chromatin structure assay) in males from infertile couples (n= 293). The results showed that semen contaminations with the investigated bacterial species were not associated with sperm DNA fragmentation. However, contaminations with Mycoplasma spp. and C center dot trachomatis were associated with decreased spermconcentrations. Total sperm numbers in contaminated semen samples tended to be decreased, but not significantly. Mycoplasma had the highest adverse effect on sperm quality (concentration, motility, morphology and DNA condensation). Antibi
Název v anglickém jazyce
The effect of bacterial contamination of semen on sperm chromatin integrity and standard semen parameters in men from infertile couples
Popis výsledku anglicky
A considerable proportion of male factor infertility cases are associated with inflammatory processes. The most common sexually transmissible agents causing sexually transmitted diseases in industrial countries are Chlamydia trachomatis, genital Ureaplasma and Mycoplasma spp. This study was undertaken to investigate whether these bacterial contaminants in semen affect sperm quality parameters and particularly DNA integrity (detected by sperm chromatin structure assay) in males from infertile couples (n= 293). The results showed that semen contaminations with the investigated bacterial species were not associated with sperm DNA fragmentation. However, contaminations with Mycoplasma spp. and C center dot trachomatis were associated with decreased spermconcentrations. Total sperm numbers in contaminated semen samples tended to be decreased, but not significantly. Mycoplasma had the highest adverse effect on sperm quality (concentration, motility, morphology and DNA condensation). Antibi
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EB - Genetika a molekulární biologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NT11083" target="_blank" >NT11083: Selekce funkčních spermií pomocí vybraných biomarkerů v diagnostice mužské neplodnosti</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
ANDROLOGIA
ISSN
0303-4569
e-ISSN
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Svazek periodika
44
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
9
Strana od-do
410-418
Kód UT WoS článku
000304439300056
EID výsledku v databázi Scopus
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