The phenotype and activation status of T and NK cells in porcine colostrum suggest these are central/effector memory cells

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F14%3A%230001101" target="_blank" >RIV/00027162:_____/14:#0001101 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.tvjl.2014.09.008" target="_blank" >http://dx.doi.org/10.1016/j.tvjl.2014.09.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.tvjl.2014.09.008" target="_blank" >10.1016/j.tvjl.2014.09.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The phenotype and activation status of T and NK cells in porcine colostrum suggest these are central/effector memory cells

Popis výsledku v původním jazyce

In pigs, the epitheliochorial placenta does not allow transfer of maternally derived antibodies or immune cells to the fetus. Thus, piglets are dependent on intake of colostrum for acquisition of passive immunity during the neonatal period. As well as immunoglobulin G (IgG), cellular components of colostrum, mainly lymphocytes, can enter the systemic circulation and secondary lymphoid organs of the neonate. In order to understand the function and immunological role of these cells, a flow cytometric study was undertaken to characterise the cellular profile and phenotype of T cells and NK cells present in porcine colostrum. The results indicated that the greatest numbers of lymphocytes were found on the first day of lactation. The predominant cell typesin colostrum were CD8(+) single positive T cells (53.6%), followed by CD4(+)CD8(+) double positive T cells (21.1%), CD2(+)CD8(+) gamma delta T cells (15.0%) and NK cells (13.5%). CD4(+) single positive T cells (4.4%) and other gamma delta

Název v anglickém jazyce

The phenotype and activation status of T and NK cells in porcine colostrum suggest these are central/effector memory cells

Popis výsledku anglicky

In pigs, the epitheliochorial placenta does not allow transfer of maternally derived antibodies or immune cells to the fetus. Thus, piglets are dependent on intake of colostrum for acquisition of passive immunity during the neonatal period. As well as immunoglobulin G (IgG), cellular components of colostrum, mainly lymphocytes, can enter the systemic circulation and secondary lymphoid organs of the neonate. In order to understand the function and immunological role of these cells, a flow cytometric study was undertaken to characterise the cellular profile and phenotype of T cells and NK cells present in porcine colostrum. The results indicated that the greatest numbers of lymphocytes were found on the first day of lactation. The predominant cell typesin colostrum were CD8(+) single positive T cells (53.6%), followed by CD4(+)CD8(+) double positive T cells (21.1%), CD2(+)CD8(+) gamma delta T cells (15.0%) and NK cells (13.5%). CD4(+) single positive T cells (4.4%) and other gamma delta

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

<a href="/cs/project/LO1218" target="_blank" >LO1218: Zdravé zvíře jako zdroj zdravé potraviny</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinary Journal

ISSN

1090-0233

e-ISSN

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Svazek periodika

202

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

477-482

Kód UT WoS článku

000348017500014

EID výsledku v databázi Scopus

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