Foodborne viruses - molecular epidemiology in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F18%3AN0000094" target="_blank" >RIV/00027162:_____/18:N0000094 - isvavai.cz</a>

Výsledek na webu

<a href="https://wet.asu.edu/wp-content/uploads/2018/10/AbstractsISFEV.pdf" target="_blank" >https://wet.asu.edu/wp-content/uploads/2018/10/AbstractsISFEV.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Foodborne viruses - molecular epidemiology in the Czech Republic

Popis výsledku v původním jazyce

6th Food and Environmental Virology Conference, 7-10.10.2018. Arizona, USA. The number of foodborne outbreaks caused by viruses increased in the EU. In spite of it, the viruses are rarely determined as causes of food- or waterborne outbreaks in the Czech Republic (CZ; Fig. 1). The unpreparedness of the national surveillance system for foodborne diseases was revealed during a norovirus (NoV) waterborne outbreak (4,021 human cases) in 2015, Prague. The main problem was the amble determination of the causative agents and the source of the contamination. Therefore national project “Foodborne viruses – molecular epidemiology and methods for rapid detection” has been initiated. The main aims of the project are development/introduction of rapid multiplex one-step screening methods together with analysis of genomes of selected foodborne viruses. Sequence and phylogenetic analyses are used for epidemiological studies as well as for the creation of a database of viral strains circulating in the CZ. Up to date a total of 400 partial sequences of HAV (VP1/2A) and 57 of NoV (ORF1/ORF2, RdPd) originating from human patients and environment, and 284 of HEV (ORF1) from human patients, domestic pigs and wild boars were analysed. Sequence analyses confirmed by epidemiological data provided clear evidence of the relationship between the agents and resulting infection; zoonotic transmission of HEV, NoV food- and waterborne outbreaks, discrimination between related HAV outbreaks and transmission of HAV by blood transfusion. The results emanating from this project improve our understanding regarding the prevalence and ecology of foodborne viruses in the CZ and strengthen the cooperation between human and veterinary laboratories and Regional Public Health Authorities.

Název v anglickém jazyce

Foodborne viruses - molecular epidemiology in the Czech Republic

Popis výsledku anglicky

6th Food and Environmental Virology Conference, 7-10.10.2018. Arizona, USA. The number of foodborne outbreaks caused by viruses increased in the EU. In spite of it, the viruses are rarely determined as causes of food- or waterborne outbreaks in the Czech Republic (CZ; Fig. 1). The unpreparedness of the national surveillance system for foodborne diseases was revealed during a norovirus (NoV) waterborne outbreak (4,021 human cases) in 2015, Prague. The main problem was the amble determination of the causative agents and the source of the contamination. Therefore national project “Foodborne viruses – molecular epidemiology and methods for rapid detection” has been initiated. The main aims of the project are development/introduction of rapid multiplex one-step screening methods together with analysis of genomes of selected foodborne viruses. Sequence and phylogenetic analyses are used for epidemiological studies as well as for the creation of a database of viral strains circulating in the CZ. Up to date a total of 400 partial sequences of HAV (VP1/2A) and 57 of NoV (ORF1/ORF2, RdPd) originating from human patients and environment, and 284 of HEV (ORF1) from human patients, domestic pigs and wild boars were analysed. Sequence analyses confirmed by epidemiological data provided clear evidence of the relationship between the agents and resulting infection; zoonotic transmission of HEV, NoV food- and waterborne outbreaks, discrimination between related HAV outbreaks and transmission of HAV by blood transfusion. The results emanating from this project improve our understanding regarding the prevalence and ecology of foodborne viruses in the CZ and strengthen the cooperation between human and veterinary laboratories and Regional Public Health Authorities.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

30302 - Epidemiology

Projekt

<a href="/cs/project/NV17-31921A" target="_blank" >NV17-31921A: Viry v souvislosti s alimentárními infekcemi – molekulární epidemiologie a metody rychlé detekce</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů