Effects of different pharmaceutical residues on embryos of fish species native to Central Europe

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000006" target="_blank" >RIV/00027162:_____/22:N0000006 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/22:43920569 RIV/62157124:16270/22:43880175

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0045653521033877" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0045653521033877</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chemosphere.2021.132915" target="_blank" >10.1016/j.chemosphere.2021.132915</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effects of different pharmaceutical residues on embryos of fish species native to Central Europe

Popis výsledku v původním jazyce

Concentrations of pharmacologically active substance residues are increasing dramatically throughout the world and are considered to be serious danger for the aquatic environment. Recent surveys have shown that these substances can cause negative effects to non-target organisms. High occurrence of residues in the aquatic environment is due to increasing prescription and consumption of drugs, discharge in wastewater and its imperfect purification in wastewater treatment plants. In the present study, we tested the effects of commonly used pharmacologically active substances such as antibiotics, analgesics and antidepressants, on embryonic stages of fish. In particular, concentration range of tramadol, enrofloxacine and nortriptylin was tested on zebrafish (Danio rerio; common toxicological model organism), common carp (Cyprinus carpio), catfish (Silurus glanis), and tench (Tinca tinca) ¬– species native to freshwaters of central Europe. Even though the effects on hatching, mortality and malformation occurence were observed only in the high tested concentrations, the results of the gene expression show, that even the low, environmentally relevant concentrations of pharmaceutical residue can cause signifficant changes in embryo early development.

Název v anglickém jazyce

Effects of different pharmaceutical residues on embryos of fish species native to Central Europe

Popis výsledku anglicky

Concentrations of pharmacologically active substance residues are increasing dramatically throughout the world and are considered to be serious danger for the aquatic environment. Recent surveys have shown that these substances can cause negative effects to non-target organisms. High occurrence of residues in the aquatic environment is due to increasing prescription and consumption of drugs, discharge in wastewater and its imperfect purification in wastewater treatment plants. In the present study, we tested the effects of commonly used pharmacologically active substances such as antibiotics, analgesics and antidepressants, on embryonic stages of fish. In particular, concentration range of tramadol, enrofloxacine and nortriptylin was tested on zebrafish (Danio rerio; common toxicological model organism), common carp (Cyprinus carpio), catfish (Silurus glanis), and tench (Tinca tinca) ¬– species native to freshwaters of central Europe. Even though the effects on hatching, mortality and malformation occurence were observed only in the high tested concentrations, the results of the gene expression show, that even the low, environmentally relevant concentrations of pharmaceutical residue can cause signifficant changes in embryo early development.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Udržitelná produkce zdravých ryb v různých akvakulturních systémech - PROFISH</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemosphere

ISSN

0045-6535

e-ISSN

1879-1298

Svazek periodika

291

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

12

Strana od-do

—

Kód UT WoS článku

000757983200005

EID výsledku v databázi Scopus

2-s2.0-85119269920