Development of a system evaluating three qualitative aspects of antimicrobial use in dairy cows on farms and appreciating targeted treatment of mastitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F24%3AN0000016" target="_blank" >RIV/00027162:_____/24:N0000016 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Development of a system evaluating three qualitative aspects of antimicrobial use in dairy cows on farms and appreciating targeted treatment of mastitis

Popis výsledku v původním jazyce

In the Czech Republic, similarly to the countries with highly developed farming systems, the largest part of antimicrobial use (AMU) in the sector of dairy cattle is associated with mastitis treatment and control. Minimising the incidence of mastitis and its targeted treatment thus represents the greatest potential for AMU reduction. The system, serving as a tool that utilises data on AMU and udder health monitoring for the complex evaluation of dairy farms, began to be built two years ago. The system will use DLN Cattle software as the AMU data source (already built and noted on the AACTING web). It is intended to evaluate the total quantity of AMU by counting treatment courses (i.e. the use of one AM VMP in one quarter or on an animal via another route), but it also includes three qualitative aspects in each treatment course: 1) EMA-AMEG category of an antimicrobial (AM); 2) Czech "Prudent use regimen classification“; 3) number of antimicrobials per one veterinary medicinal product (VMP) - monocomponent VMPs should be preferred; both injectable (one or two AMs) and intramammary (one or two to four AMs) antimicrobial VMPs will be specifically considered and scored. Malus points will be applied for the use of antimicrobials based on the above 3 aspects. It means that for aspect “1” AMEG, AM are scored as D, C, B with a malus of 10, 20 and 30, respectively. For aspect “2”, VMPs classified as under “prudent use regimen” will incur additional 10 malus points. The last scoring aspect “3” which considers the number of AMs per VMP, will assign full points to the AM from the highest AMEG category among AM in the VMP. For the second, third or fourth component, only half the points will be counted (three-component VMP from D + C category should not be scored more prudently than a monocomponent one from B category). All VMPs containing antimicrobials within the scope of obligatory reported ATCvet codes as defined by the Annex of the Commission Delegated Act (EU)2021/578 will be considered in the scoring system. The subsequent part of the system is specifically designed to address targeted mastitis therapy during lactation and drying off. Once the treatment in lactation begins, 40% of malus points will be removed, if there is proof of a pathogen (= treatment will be targeted). Drying off performed without AM will be awarded by 5 bonus points per quarter (i.e. a maximum of 20 bonus points per cow without AM). Udder health scoring will be evaluated according to the test-day somatic cell count (SCC) from milk recording (MR). The frequency of new infections a) during lactation, b) between the last MR test before drying off and the first MR test after delivery will be the main parameters derived from the SCC. Data will be summarised quarterly and made available online for the participants. The planned formal outcomes structure per AMU is as follows: A) Number of treatment courses per 100 cows/year (=36500 feeding days); B) Scoring points per 100 cows/year (including sum, malus and bonus points separately); C) Subgroup “Czech Prudent Use” will be visible separately. Further scoring related to udder health will also be visible for management purposes. Conclusion The developed system should comprehensively evaluate not only the quantity and quality of AMU, but also assess targeting of the mastitis treatment and udder health. During the pilot phase, ranking will be conducted among the farms participating voluntarily, and they will be finally classified into three certification categories. If it becomes more widespread within the dairy sector, it could also be linked with subsidy systems.

Název v anglickém jazyce

Development of a system evaluating three qualitative aspects of antimicrobial use in dairy cows on farms and appreciating targeted treatment of mastitis

Popis výsledku anglicky

In the Czech Republic, similarly to the countries with highly developed farming systems, the largest part of antimicrobial use (AMU) in the sector of dairy cattle is associated with mastitis treatment and control. Minimising the incidence of mastitis and its targeted treatment thus represents the greatest potential for AMU reduction. The system, serving as a tool that utilises data on AMU and udder health monitoring for the complex evaluation of dairy farms, began to be built two years ago. The system will use DLN Cattle software as the AMU data source (already built and noted on the AACTING web). It is intended to evaluate the total quantity of AMU by counting treatment courses (i.e. the use of one AM VMP in one quarter or on an animal via another route), but it also includes three qualitative aspects in each treatment course: 1) EMA-AMEG category of an antimicrobial (AM); 2) Czech "Prudent use regimen classification“; 3) number of antimicrobials per one veterinary medicinal product (VMP) - monocomponent VMPs should be preferred; both injectable (one or two AMs) and intramammary (one or two to four AMs) antimicrobial VMPs will be specifically considered and scored. Malus points will be applied for the use of antimicrobials based on the above 3 aspects. It means that for aspect “1” AMEG, AM are scored as D, C, B with a malus of 10, 20 and 30, respectively. For aspect “2”, VMPs classified as under “prudent use regimen” will incur additional 10 malus points. The last scoring aspect “3” which considers the number of AMs per VMP, will assign full points to the AM from the highest AMEG category among AM in the VMP. For the second, third or fourth component, only half the points will be counted (three-component VMP from D + C category should not be scored more prudently than a monocomponent one from B category). All VMPs containing antimicrobials within the scope of obligatory reported ATCvet codes as defined by the Annex of the Commission Delegated Act (EU)2021/578 will be considered in the scoring system. The subsequent part of the system is specifically designed to address targeted mastitis therapy during lactation and drying off. Once the treatment in lactation begins, 40% of malus points will be removed, if there is proof of a pathogen (= treatment will be targeted). Drying off performed without AM will be awarded by 5 bonus points per quarter (i.e. a maximum of 20 bonus points per cow without AM). Udder health scoring will be evaluated according to the test-day somatic cell count (SCC) from milk recording (MR). The frequency of new infections a) during lactation, b) between the last MR test before drying off and the first MR test after delivery will be the main parameters derived from the SCC. Data will be summarised quarterly and made available online for the participants. The planned formal outcomes structure per AMU is as follows: A) Number of treatment courses per 100 cows/year (=36500 feeding days); B) Scoring points per 100 cows/year (including sum, malus and bonus points separately); C) Subgroup “Czech Prudent Use” will be visible separately. Further scoring related to udder health will also be visible for management purposes. Conclusion The developed system should comprehensively evaluate not only the quantity and quality of AMU, but also assess targeting of the mastitis treatment and udder health. During the pilot phase, ranking will be conducted among the farms participating voluntarily, and they will be finally classified into three certification categories. If it becomes more widespread within the dairy sector, it could also be linked with subsidy systems.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/QK22020292" target="_blank" >QK22020292: Certifikace chovů dojeného skotu dle spotřeby antimikrobik a zdraví mléčné žlázy ke snížení jejich spotřeby, racionalizaci jejich používání a tlumení rezistence k nim</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů