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The V6-V1 interpeak interval: a novel criterion for the diagnosis of left bundle branch capture

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F22%3A43921795" target="_blank" >RIV/00064173:_____/22:43921795 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/00216208:11120/22:43921795

  • Výsledek na webu

    <a href="https://doi.org/10.1093/europace/euab164" target="_blank" >https://doi.org/10.1093/europace/euab164</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1093/europace/euab164" target="_blank" >10.1093/europace/euab164</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    The V6-V1 interpeak interval: a novel criterion for the diagnosis of left bundle branch capture

  • Popis výsledku v původním jazyce

    AIMS: We hypothesized that during left bundle branch (LBB) area pacing, the various possible combinations of direct capture/non-capture of the septal myocardium and the LBB result in distinct patterns of right and left ventricular activation. This could translate into different combinations of R-wave peak time (RWPT) in V1 and V6. Consequently, the V6-V1 interpeak interval could differentiate the three types of LBB area capture: non-selective (ns-)LBB, selective (s-)LBB, and left ventricular septal (LVS). METHODS AND RESULTS: Patients with unquestionable evidence of LBB capture were included. The V6-V1 interpeak interval, V6RWPT, and V1RWPT were compared between different types of LBB area capture. A total of 468 patients from two centres were screened, with 124 patients (239 electrocardiograms) included in the analysis. Loss of LVS capture resulted in an increase in V1RWPT by &gt;=15 ms but did not impact V6RWPT. Loss of LBB capture resulted in an increase in V6RWPT by &gt;=15 ms but only minimally influenced V1RWPT. Consequently, the V6-V1 interval was longest during s-LBB capture (62.3 +- 21.4 ms), intermediate during ns-LBB capture (41.3 +- 14.0 ms), and shortest during LVS capture (26.5 +- 8.6 ms). The optimal value of the V6-V1 interval value for the differentiation between ns-LBB and LVS capture was 33 ms (area under the receiver operating characteristic curve of 84.7%). A specificity of 100% for the diagnosis of LBB capture was obtained with a cut-off value of &gt;44 ms. CONCLUSION: The V6-V1 interpeak interval is a promising novel criterion for the diagnosis of LBB area capture.

  • Název v anglickém jazyce

    The V6-V1 interpeak interval: a novel criterion for the diagnosis of left bundle branch capture

  • Popis výsledku anglicky

    AIMS: We hypothesized that during left bundle branch (LBB) area pacing, the various possible combinations of direct capture/non-capture of the septal myocardium and the LBB result in distinct patterns of right and left ventricular activation. This could translate into different combinations of R-wave peak time (RWPT) in V1 and V6. Consequently, the V6-V1 interpeak interval could differentiate the three types of LBB area capture: non-selective (ns-)LBB, selective (s-)LBB, and left ventricular septal (LVS). METHODS AND RESULTS: Patients with unquestionable evidence of LBB capture were included. The V6-V1 interpeak interval, V6RWPT, and V1RWPT were compared between different types of LBB area capture. A total of 468 patients from two centres were screened, with 124 patients (239 electrocardiograms) included in the analysis. Loss of LVS capture resulted in an increase in V1RWPT by &gt;=15 ms but did not impact V6RWPT. Loss of LBB capture resulted in an increase in V6RWPT by &gt;=15 ms but only minimally influenced V1RWPT. Consequently, the V6-V1 interval was longest during s-LBB capture (62.3 +- 21.4 ms), intermediate during ns-LBB capture (41.3 +- 14.0 ms), and shortest during LVS capture (26.5 +- 8.6 ms). The optimal value of the V6-V1 interval value for the differentiation between ns-LBB and LVS capture was 33 ms (area under the receiver operating characteristic curve of 84.7%). A specificity of 100% for the diagnosis of LBB capture was obtained with a cut-off value of &gt;44 ms. CONCLUSION: The V6-V1 interpeak interval is a promising novel criterion for the diagnosis of LBB area capture.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    30201 - Cardiac and Cardiovascular systems

Návaznosti výsledku

  • Projekt

  • Návaznosti

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2022

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    EP Europace

  • ISSN

    1099-5129

  • e-ISSN

    1532-2092

  • Svazek periodika

    24

  • Číslo periodika v rámci svazku

    1

  • Stát vydavatele periodika

    GB - Spojené království Velké Británie a Severního Irska

  • Počet stran výsledku

    8

  • Strana od-do

    40-47

  • Kód UT WoS článku

    000743688600009

  • EID výsledku v databázi Scopus

    2-s2.0-85118588119