Efficacy and Safety of Deep Sclerectomy with the Esnoper Clip Implant for Uncontrolled Primary Open Angle Glaucoma: A One Year Prospective Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F23%3A43924093" target="_blank" >RIV/00064173:_____/23:43924093 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/23:43924093

Výsledek na webu

<a href="https://doi.org/10.1097/IJG.0000000000002137" target="_blank" >https://doi.org/10.1097/IJG.0000000000002137</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/IJG.0000000000002137" target="_blank" >10.1097/IJG.0000000000002137</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Efficacy and Safety of Deep Sclerectomy with the Esnoper Clip Implant for Uncontrolled Primary Open Angle Glaucoma: A One Year Prospective Study

Popis výsledku v původním jazyce

PRCIS: Deep sclerectomy (DS) with the Esnoper Clip(R) drainage implant in patients with uncontrolled primary open-angle glaucoma (POAG) achieved a complete success rate of 87.2% at the one-year follow-up. PURPOSE: To investigate the efficacy and safety of DS followed by Esnoper Clip(R) implantation in patients with uncontrolled POAG. METHODS: In a prospective, consecutive, interventional study, we investigated 39 eyes of 35 patients with uncontrolled POAG who underwent DS with Esnoper Clip(R) implantation. Complete ophthalmologic examinations including corrected visual acuity (BCVA) and intraocular pressure (IOP), were performed preoperatively, and at 1 day, at 1 week as well as at 1, 3, 6, 9 and 12 months postoperatively. Moreover, any goniopunctures and glaucoma medications required postoperatively were noted. RESULTS: The mean preoperative IOP was 20.8+-5.2 mm Hg and it decreased to 13.9+-3.1 mm Hg at one year postoperatively (P&lt;0.001). The number of glaucoma medications decreased from 2.9+-0.7 preoperatively to 0.3+-0.8 after one year (P&lt;0.001). The complete success (CS) rate (IOP&lt;=21 mm Hg without glaucoma medication) and the qualified success (QS) rate (IOP&lt;=21 mm Hg with or without glaucoma medication) were 87.2% and 94.9%, respectively. Goniopuncture was performed in 33.3% of cases. No significant BCVA changes were registered at the final follow-up. Perioperative complications consisted of 3 micro-perforations of the trabeculo-descemet membrane. Postoperative complications included: hyphema (6 eyes), hypotony (6 eyes), shallow anterior chamber (3 eyes), choroidal detachment (4 eyes)-all of which were resolved without surgical intervention during the first postoperative month--and conjunctival dehiscence, which required re-suture (2 eyes). CONCLUSION: Deep sclerectomy with the Esnoper Clip(R) implant was safe and effectively lowered intraocular pressure in patients with uncontrolled primary open-angle glaucoma.

Název v anglickém jazyce

Efficacy and Safety of Deep Sclerectomy with the Esnoper Clip Implant for Uncontrolled Primary Open Angle Glaucoma: A One Year Prospective Study

Popis výsledku anglicky

PRCIS: Deep sclerectomy (DS) with the Esnoper Clip(R) drainage implant in patients with uncontrolled primary open-angle glaucoma (POAG) achieved a complete success rate of 87.2% at the one-year follow-up. PURPOSE: To investigate the efficacy and safety of DS followed by Esnoper Clip(R) implantation in patients with uncontrolled POAG. METHODS: In a prospective, consecutive, interventional study, we investigated 39 eyes of 35 patients with uncontrolled POAG who underwent DS with Esnoper Clip(R) implantation. Complete ophthalmologic examinations including corrected visual acuity (BCVA) and intraocular pressure (IOP), were performed preoperatively, and at 1 day, at 1 week as well as at 1, 3, 6, 9 and 12 months postoperatively. Moreover, any goniopunctures and glaucoma medications required postoperatively were noted. RESULTS: The mean preoperative IOP was 20.8+-5.2 mm Hg and it decreased to 13.9+-3.1 mm Hg at one year postoperatively (P&lt;0.001). The number of glaucoma medications decreased from 2.9+-0.7 preoperatively to 0.3+-0.8 after one year (P&lt;0.001). The complete success (CS) rate (IOP&lt;=21 mm Hg without glaucoma medication) and the qualified success (QS) rate (IOP&lt;=21 mm Hg with or without glaucoma medication) were 87.2% and 94.9%, respectively. Goniopuncture was performed in 33.3% of cases. No significant BCVA changes were registered at the final follow-up. Perioperative complications consisted of 3 micro-perforations of the trabeculo-descemet membrane. Postoperative complications included: hyphema (6 eyes), hypotony (6 eyes), shallow anterior chamber (3 eyes), choroidal detachment (4 eyes)-all of which were resolved without surgical intervention during the first postoperative month--and conjunctival dehiscence, which required re-suture (2 eyes). CONCLUSION: Deep sclerectomy with the Esnoper Clip(R) implant was safe and effectively lowered intraocular pressure in patients with uncontrolled primary open-angle glaucoma.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Glaucoma

ISSN

1057-0829

e-ISSN

1536-481X

Svazek periodika

32

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

227-235

Kód UT WoS článku

000944073100013

EID výsledku v databázi Scopus

2-s2.0-85149823676