Spinal fusion for single-level SPECT/CT positive lumbar degenerative disc disease: the SPINUS I study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F23%3A43925813" target="_blank" >RIV/00064173:_____/23:43925813 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61383082:_____/23:00001296 RIV/00216208:11110/23:10465267 RIV/00216208:11120/23:43925813 RIV/00064203:_____/23:10465267

Výsledek na webu

<a href="https://doi.org/10.1007/s00701-023-05666-8" target="_blank" >https://doi.org/10.1007/s00701-023-05666-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00701-023-05666-8" target="_blank" >10.1007/s00701-023-05666-8</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spinal fusion for single-level SPECT/CT positive lumbar degenerative disc disease: the SPINUS I study

Popis výsledku v původním jazyce

INTRODUCTION AND PURPOSE: With current imaging modalities and diagnostic tests, identifying pain generators in patients with non-specific chronic low back pain (CLBP) is difficult. There is growing evidence of the effectiveness of SPECT/CT examination in diagnosing the source of pain in the spine. The study aims to investigate the effect of posterior interbody fusion on a single-level SPECT/CT positive lumbar degenerative disc disease (DDD). MATERIAL AND METHODS: This is a prospective study of patients with chronic low back pain (CLBP) operated on for a single-level SPECT/CT positive DDD. Primary outcomes were changes in visual analogue scale (VAS) scores and the Oswestry Disability Index (ODI). Secondary outcomes were complications, return to work, satisfaction and willingness to re-undergo surgery. RESULTS: During a 3-year period, 38 patients underwent single-level fusion surgery. The mean preoperative VAS score of 8.4 (+- 1.1) decreased to 3.2 (+- 2.5, p &lt; 0.001) and the mean preoperative ODI of 51.5 (+- 7.3) improved to 20.7 (+- 14.68, p &lt; 0.001) at a 2-year follow-up. A minimum clinically important difference (30% reduction in VAS and ODI) was achieved in 84.2% of patients. Some 71% of patients were satisfied with the surgery results and 89.4% would undergo surgery again. There were four complications, and two patients underwent revision surgery. Some 82.9% of patients returned to work. CONCLUSION: Fusion for one-level SPECT/CT positive lumbar DDD resulted in substantial clinical improvement and satisfaction with surgical treatment. Therefore, SPECT/CT imaging could be useful in assessing patients with CLBP, especially those with unclear MRI findings. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04876586.

Název v anglickém jazyce

Spinal fusion for single-level SPECT/CT positive lumbar degenerative disc disease: the SPINUS I study

Popis výsledku anglicky

INTRODUCTION AND PURPOSE: With current imaging modalities and diagnostic tests, identifying pain generators in patients with non-specific chronic low back pain (CLBP) is difficult. There is growing evidence of the effectiveness of SPECT/CT examination in diagnosing the source of pain in the spine. The study aims to investigate the effect of posterior interbody fusion on a single-level SPECT/CT positive lumbar degenerative disc disease (DDD). MATERIAL AND METHODS: This is a prospective study of patients with chronic low back pain (CLBP) operated on for a single-level SPECT/CT positive DDD. Primary outcomes were changes in visual analogue scale (VAS) scores and the Oswestry Disability Index (ODI). Secondary outcomes were complications, return to work, satisfaction and willingness to re-undergo surgery. RESULTS: During a 3-year period, 38 patients underwent single-level fusion surgery. The mean preoperative VAS score of 8.4 (+- 1.1) decreased to 3.2 (+- 2.5, p &lt; 0.001) and the mean preoperative ODI of 51.5 (+- 7.3) improved to 20.7 (+- 14.68, p &lt; 0.001) at a 2-year follow-up. A minimum clinically important difference (30% reduction in VAS and ODI) was achieved in 84.2% of patients. Some 71% of patients were satisfied with the surgery results and 89.4% would undergo surgery again. There were four complications, and two patients underwent revision surgery. Some 82.9% of patients returned to work. CONCLUSION: Fusion for one-level SPECT/CT positive lumbar DDD resulted in substantial clinical improvement and satisfaction with surgical treatment. Therefore, SPECT/CT imaging could be useful in assessing patients with CLBP, especially those with unclear MRI findings. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04876586.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Neurochirurgica

ISSN

0001-6268

e-ISSN

0942-0940

Svazek periodika

165

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

8

Strana od-do

2633-2640

Kód UT WoS článku

001014493100001

EID výsledku v databázi Scopus

2-s2.0-85163029580