Additional factors underlying pacing induced cardiomyopathy in patients underwent right ventricular pacing and his bundle pacing. Author's reply

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43926201" target="_blank" >RIV/00064173:_____/24:43926201 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/24:43926201

Výsledek na webu

<a href="https://journals.viamedica.pl/kardiologia_polska/article/view/97882" target="_blank" >https://journals.viamedica.pl/kardiologia_polska/article/view/97882</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33963/v.kp.97882" target="_blank" >10.33963/v.kp.97882</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Additional factors underlying pacing induced cardiomyopathy in patients underwent right ventricular pacing and his bundle pacing. Author's reply

Popis výsledku v původním jazyce

We agree that concomitant diseases such as cardiac sarcoidosis (CS) and amyloidosis (CA) might influence the clinical course of patients with bradycardia. The clinical spectrum of transthyretin cardiac amyloidosis (ATTR-CA) symptoms includes advanced conduction disorders requiring pacemaker implantation. It had been documented that 3%-13% of patients with ATTR-CA had pacemakers implanted before they were diagnosed with CA. However, in the European population, the prevalence of ATTR-CA in pacemaker patients was very low (only 2%). Cardiac sarcoidosis (CS) also leads to advanced symptomatic atrioventricular blocks, and according to Kandolin et al., it was the first symptom in up to 44% of patients with diagnosed CS. However, the prevalence of CS remains very low in the European population, where it is a rare condition. We initiate further diagnostic steps only if other risk factors are present. Therefore, we believe that the low prevalence of these diseases and the randomized study design should not affect the differences in the left ventricular ejection fraction between studied groups. On the other hand, we agree that due to the pathophysiology of the diseases, scanning for CS and CA could be helpful while measuring the markers of collagen metabolism.

Název v anglickém jazyce

Additional factors underlying pacing induced cardiomyopathy in patients underwent right ventricular pacing and his bundle pacing. Author's reply

Popis výsledku anglicky

We agree that concomitant diseases such as cardiac sarcoidosis (CS) and amyloidosis (CA) might influence the clinical course of patients with bradycardia. The clinical spectrum of transthyretin cardiac amyloidosis (ATTR-CA) symptoms includes advanced conduction disorders requiring pacemaker implantation. It had been documented that 3%-13% of patients with ATTR-CA had pacemakers implanted before they were diagnosed with CA. However, in the European population, the prevalence of ATTR-CA in pacemaker patients was very low (only 2%). Cardiac sarcoidosis (CS) also leads to advanced symptomatic atrioventricular blocks, and according to Kandolin et al., it was the first symptom in up to 44% of patients with diagnosed CS. However, the prevalence of CS remains very low in the European population, where it is a rare condition. We initiate further diagnostic steps only if other risk factors are present. Therefore, we believe that the low prevalence of these diseases and the randomized study design should not affect the differences in the left ventricular ejection fraction between studied groups. On the other hand, we agree that due to the pathophysiology of the diseases, scanning for CS and CA could be helpful while measuring the markers of collagen metabolism.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polish Heart Journal - Kardiologia Polska

ISSN

0022-9032

e-ISSN

1897-4279

Svazek periodika

82

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

2

Strana od-do

117-118

Kód UT WoS článku

001162376000001

EID výsledku v databázi Scopus

2-s2.0-85183965101