Influence of small-volume liposuction on metabolic syndrome conditions - a prospective study of 12 patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F25%3A43928368" target="_blank" >RIV/00064173:_____/25:43928368 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/25:00143829 RIV/00216208:11120/25:43928368 RIV/00159816:_____/25:00082428

Výsledek na webu

<a href="https://doi.org/10.1016/j.jpra.2025.04.006" target="_blank" >https://doi.org/10.1016/j.jpra.2025.04.006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jpra.2025.04.006" target="_blank" >10.1016/j.jpra.2025.04.006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Influence of small-volume liposuction on metabolic syndrome conditions - a prospective study of 12 patients

Popis výsledku v původním jazyce

Introduction: Liposuction is a surgical method for fat aspiration, which reduces the amount of subcutaneous fat. Adipose tissue is important in regulating insulin sensitivity, and its excess, especially in the form of intra-abdominal fat, is associated with a higher risk of the development of metabolic syndrome. Clinical findings associated with metabolic syndrome include central obesity, dyslipidemia, insulin resistance, hypertension, and atherosclerotic disease. Nevertheless, it is not yet clear what long-term metabolic changes might be influenced by the liposuction. The aim of our study was to analyze the effects of liposuction on the lipid profile, arterial blood pressure, and glucose metabolism in healthy women. Patients and methods: 12 patients who underwent liposuction were included in the study. The blood pressures, arterial blood pressure, and lipid profiles were measured before surgery and approximately one year after surgery. In addition, insulin sensitivities were measured by using an oral glucose tolerance test. The results: In the long term, liposuction led to a slight reduction of body fat (p &lt; 0.05) but did not affect the blood pressure or insulin sensitivity. Although the total cholesterol and low-density lipoprotein (LDL) cholesterols were reduced, these decreases were not statistically significant. Discussion: The results of the study are consistent with some of the published data, which indicated a slight decrease in blood lipids.Conclusion: Liposuction with a small aspirate volume does not seem to induce any significant metabolic changes. A larger cohort and longer follow-ups are needed to evaluate the effects on the lipid profile, blood pressure, and glucose metabolism of the patients being studied.

Název v anglickém jazyce

Influence of small-volume liposuction on metabolic syndrome conditions - a prospective study of 12 patients

Popis výsledku anglicky

Introduction: Liposuction is a surgical method for fat aspiration, which reduces the amount of subcutaneous fat. Adipose tissue is important in regulating insulin sensitivity, and its excess, especially in the form of intra-abdominal fat, is associated with a higher risk of the development of metabolic syndrome. Clinical findings associated with metabolic syndrome include central obesity, dyslipidemia, insulin resistance, hypertension, and atherosclerotic disease. Nevertheless, it is not yet clear what long-term metabolic changes might be influenced by the liposuction. The aim of our study was to analyze the effects of liposuction on the lipid profile, arterial blood pressure, and glucose metabolism in healthy women. Patients and methods: 12 patients who underwent liposuction were included in the study. The blood pressures, arterial blood pressure, and lipid profiles were measured before surgery and approximately one year after surgery. In addition, insulin sensitivities were measured by using an oral glucose tolerance test. The results: In the long term, liposuction led to a slight reduction of body fat (p &lt; 0.05) but did not affect the blood pressure or insulin sensitivity. Although the total cholesterol and low-density lipoprotein (LDL) cholesterols were reduced, these decreases were not statistically significant. Discussion: The results of the study are consistent with some of the published data, which indicated a slight decrease in blood lipids.Conclusion: Liposuction with a small aspirate volume does not seem to induce any significant metabolic changes. A larger cohort and longer follow-ups are needed to evaluate the effects on the lipid profile, blood pressure, and glucose metabolism of the patients being studied.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JPRAS Open

ISSN

2352-5878

e-ISSN

2352-5878

Svazek periodika

45

Číslo periodika v rámci svazku

September

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

13

Strana od-do

42-54

Kód UT WoS článku

001498398600002

EID výsledku v databázi Scopus

2-s2.0-105005468567