The NOFLO Trial: Low-Flow Nasal Prongs Therapy in Weaning Nasal Continuous Positive Airway Pressure in Preterm Infants

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F13%3A%230000671" target="_blank" >RIV/00064190:_____/13:#0000671 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jpeds.2012.12.007" target="_blank" >http://dx.doi.org/10.1016/j.jpeds.2012.12.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jpeds.2012.12.007" target="_blank" >10.1016/j.jpeds.2012.12.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The NOFLO Trial: Low-Flow Nasal Prongs Therapy in Weaning Nasal Continuous Positive Airway Pressure in Preterm Infants

Popis výsledku v původním jazyce

Objective To determine if low-flow nasal prongs therapy with room air, compared with no treatment, facilitates weaning from nasal continuous positive airway pressure (NCPAP) in very low birth weight (VLBW, birth weight < 1500 g) infants. Study design VLBW infants who received respiratory support for >= 48 hours and who were stable on NCPAP for 24 hours were eligible for inclusion in this multicenter, randomized controlled trial. On stopping NCPAP, infants were randomized to receive 1 L/min air via nasalprongs or to spontaneous breathing in room air. The primary outcome measure was failure to wean. Secondary outcome measures included length of time to failure and change in heart rate, respiratory rate, oxygen saturation, and respiratory distress score.Results Seventy-eight infants were randomized: 39 to nasal prongs and 39 to spontaneous breathing. The groups were similar at birth and at randomization. Sixteen infants (41%) in the nasal prongs group failed the weaning process compared

Název v anglickém jazyce

The NOFLO Trial: Low-Flow Nasal Prongs Therapy in Weaning Nasal Continuous Positive Airway Pressure in Preterm Infants

Popis výsledku anglicky

Objective To determine if low-flow nasal prongs therapy with room air, compared with no treatment, facilitates weaning from nasal continuous positive airway pressure (NCPAP) in very low birth weight (VLBW, birth weight < 1500 g) infants. Study design VLBW infants who received respiratory support for >= 48 hours and who were stable on NCPAP for 24 hours were eligible for inclusion in this multicenter, randomized controlled trial. On stopping NCPAP, infants were randomized to receive 1 L/min air via nasalprongs or to spontaneous breathing in room air. The primary outcome measure was failure to wean. Secondary outcome measures included length of time to failure and change in heart rate, respiratory rate, oxygen saturation, and respiratory distress score.Results Seventy-eight infants were randomized: 39 to nasal prongs and 39 to spontaneous breathing. The groups were similar at birth and at randomization. Sixteen infants (41%) in the nasal prongs group failed the weaning process compared

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FG - Pediatrie

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF PEDIATRICS

ISSN

0022-3476

e-ISSN

—

Svazek periodika

163

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

79-83

Kód UT WoS článku

000321494000018

EID výsledku v databázi Scopus

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