The effect of vitamin D on the speed and quality of pediatric fracture healing

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F24%3A10001266" target="_blank" >RIV/00064190:_____/24:10001266 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1177/18632521241299624" target="_blank" >https://doi.org/10.1177/18632521241299624</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/18632521241299624" target="_blank" >10.1177/18632521241299624</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The effect of vitamin D on the speed and quality of pediatric fracture healing

Popis výsledku v původním jazyce

Purpose: To evaluate the effect of vitamin D on the speed and quality of pediatric fracture healing.Methods: A 4-year prospective study of healthy children with shaft fractures of the forearm bones (treated with minimally invasive osteosynthesis) or femur (treated by traction or by minimally invasive osteosynthesis). All children had their vitamin D levels examined four times-at the time of the injury, 1, 3, and 5 months after the injury. Also, all children underwent radiograph follow-ups (same time as blood tests) to evaluate fracture healing. Children were, in the beginning, blindly divided into two similarly sized groups-one group was orally administered cholecalciferol throughout the follow-up, the second group was not, and we compared those groups.Results: Altogether, 63 children were included in the study-36 supplemented and 27 non-supplemented. In supplemented children, the vitamin D levels increased statistically significantly during the follow-up period, in contrast to the non-supplemented group. The fracture healing on radiographs was also statistically significantly faster and better in the supplemented group. When we divided children according to fracture type, we observed statistically significantly better fracture healing in children with forearm fractures in the supplemented group for the whole study period. In children with femoral fractures, the healing in the supplemented group was statistically significantly better after 3 months; however, after 1 and 5 months, the difference was not statistically significant.Conclusions: Based on our results, we recommend vitamin D testing and administration for children treated for forearm and femoral fractures.Level of evidence: Level I.

Název v anglickém jazyce

The effect of vitamin D on the speed and quality of pediatric fracture healing

Popis výsledku anglicky

Purpose: To evaluate the effect of vitamin D on the speed and quality of pediatric fracture healing.Methods: A 4-year prospective study of healthy children with shaft fractures of the forearm bones (treated with minimally invasive osteosynthesis) or femur (treated by traction or by minimally invasive osteosynthesis). All children had their vitamin D levels examined four times-at the time of the injury, 1, 3, and 5 months after the injury. Also, all children underwent radiograph follow-ups (same time as blood tests) to evaluate fracture healing. Children were, in the beginning, blindly divided into two similarly sized groups-one group was orally administered cholecalciferol throughout the follow-up, the second group was not, and we compared those groups.Results: Altogether, 63 children were included in the study-36 supplemented and 27 non-supplemented. In supplemented children, the vitamin D levels increased statistically significantly during the follow-up period, in contrast to the non-supplemented group. The fracture healing on radiographs was also statistically significantly faster and better in the supplemented group. When we divided children according to fracture type, we observed statistically significantly better fracture healing in children with forearm fractures in the supplemented group for the whole study period. In children with femoral fractures, the healing in the supplemented group was statistically significantly better after 3 months; however, after 1 and 5 months, the difference was not statistically significant.Conclusions: Based on our results, we recommend vitamin D testing and administration for children treated for forearm and femoral fractures.Level of evidence: Level I.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30211 - Orthopaedics

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF CHILDRENS ORTHOPAEDICS

ISSN

1863-2521

e-ISSN

1863-2548

Svazek periodika

19

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

19

Strana od-do

29-47

Kód UT WoS článku

001356393000001

EID výsledku v databázi Scopus

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