Hydration and Transparency of the Rabbit Cornea Irradiated with UVB-Doses of 0.25 J/cm(2) and 0.5 J/cm(2) Compared with Equivalent UVB Radiation Exposure Reaching the Human Cornea from Sunlight

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7049" target="_blank" >RIV/00064203:_____/11:7049 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/11:00366472 RIV/61389013:_____/11:00366472 RIV/00216208:11120/11:00003322 RIV/00216208:11130/11:7049

Výsledek na webu

<a href="http://www.ncbi.nlm.nih.gov/pubmed/21599489" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21599489</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Hydration and Transparency of the Rabbit Cornea Irradiated with UVB-Doses of 0.25 J/cm(2) and 0.5 J/cm(2) Compared with Equivalent UVB Radiation Exposure Reaching the Human Cornea from Sunlight

Popis výsledku v původním jazyce

Purpose: Exposure of the cornea to UV radiation from sunlight evokes intraocular inflammation, photokeratitis. Photokeratitis is caused by UVB radiation. It is accompanied by changes of corneal hydration and light absorption. The aim of this study was toexamine the effect of two UVB doses on corneal optics in rabbits and to compare these UVB doses with the equivalent exposure of UVB radiation reaching the human cornea from sunlight. Materials and Methods: Rabbit corneas were irradiated with a daily UVBdose of 0.25 J/cm(2) or 0.5 J/cm(2) for 4 days. One day after finishing the irradiations the rabbits were sacrificed and corneal light absorption measured using our spectrophotometrical method. Corneal hydration was examined using an ultrasonic Pachymeter every experimental day before the irradiation procedure and the last day before sacrificing the animals. Results: Changes in corneal optics appeared after the repeated exposure of the cornea to a UVB dose of 0.25 J/cm(2) and massively

Název v anglickém jazyce

Hydration and Transparency of the Rabbit Cornea Irradiated with UVB-Doses of 0.25 J/cm(2) and 0.5 J/cm(2) Compared with Equivalent UVB Radiation Exposure Reaching the Human Cornea from Sunlight

Popis výsledku anglicky

Purpose: Exposure of the cornea to UV radiation from sunlight evokes intraocular inflammation, photokeratitis. Photokeratitis is caused by UVB radiation. It is accompanied by changes of corneal hydration and light absorption. The aim of this study was toexamine the effect of two UVB doses on corneal optics in rabbits and to compare these UVB doses with the equivalent exposure of UVB radiation reaching the human cornea from sunlight. Materials and Methods: Rabbit corneas were irradiated with a daily UVBdose of 0.25 J/cm(2) or 0.5 J/cm(2) for 4 days. One day after finishing the irradiations the rabbits were sacrificed and corneal light absorption measured using our spectrophotometrical method. Corneal hydration was examined using an ultrasonic Pachymeter every experimental day before the irradiation procedure and the last day before sacrificing the animals. Results: Changes in corneal optics appeared after the repeated exposure of the cornea to a UVB dose of 0.25 J/cm(2) and massively

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FF - ORL, oftalmologie, stomatologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Eye Research

ISSN

0271-3683

e-ISSN

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Svazek periodika

36

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

607-613

Kód UT WoS článku

000291444100003

EID výsledku v databázi Scopus

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