qPET - a quantitative extension of the Deauville scale to assess response in interim FDG-PET scans in lymphoma
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10292964" target="_blank" >RIV/00064203:_____/14:10292964 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11130/14:10292964
Výsledek na webu
<a href="http://dx.doi.org/10.1007/s00259-014-2715-9" target="_blank" >http://dx.doi.org/10.1007/s00259-014-2715-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00259-014-2715-9" target="_blank" >10.1007/s00259-014-2715-9</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
qPET - a quantitative extension of the Deauville scale to assess response in interim FDG-PET scans in lymphoma
Popis výsledku v původním jazyce
Background Interim FDG-PET is used for treatment tailoring in lymphoma. Deauville response criteria consist of five ordinal categories based on visual comparison of residual tumor uptake to physiological reference uptakes. However, PET-response is a continuum and visual assessments can be distorted by optical illusions. Objectives With a novel semi-automatic quantification tool we eliminate optical illusions and extend the Deauville score to a continuous scale. Patients and methods SUVpeak of residual tumors and average uptake of the liver is measured with standardized volumes of interest. The qPET value is the quotient of these measurements. Deauville scores and qPET-values were determined in 898 pediatric Hodgkin's lymphoma patients after two OEPA chemotherapy cycles. Results Deauville categories translate to thresholds on the qPET scale: Categories 3, 4, 5 correspond to qPET values of 0.95, 1.3 and 2.0, respectively. The distribution of qPET values is unimodal with a peak representi
Název v anglickém jazyce
qPET - a quantitative extension of the Deauville scale to assess response in interim FDG-PET scans in lymphoma
Popis výsledku anglicky
Background Interim FDG-PET is used for treatment tailoring in lymphoma. Deauville response criteria consist of five ordinal categories based on visual comparison of residual tumor uptake to physiological reference uptakes. However, PET-response is a continuum and visual assessments can be distorted by optical illusions. Objectives With a novel semi-automatic quantification tool we eliminate optical illusions and extend the Deauville score to a continuous scale. Patients and methods SUVpeak of residual tumors and average uptake of the liver is measured with standardized volumes of interest. The qPET value is the quotient of these measurements. Deauville scores and qPET-values were determined in 898 pediatric Hodgkin's lymphoma patients after two OEPA chemotherapy cycles. Results Deauville categories translate to thresholds on the qPET scale: Categories 3, 4, 5 correspond to qPET values of 0.95, 1.3 and 2.0, respectively. The distribution of qPET values is unimodal with a peak representi
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FD - Onkologie a hematologie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
European Journal of Nuclear Medicine and Molecular Imaging
ISSN
1619-7070
e-ISSN
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Svazek periodika
41
Číslo periodika v rámci svazku
7
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
8
Strana od-do
1301-1308
Kód UT WoS článku
000337286200005
EID výsledku v databázi Scopus
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