Evaluation of the impact of oximeter averaging times on automated FiO(2) control in routine NICU care: a randomized cross-over study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F23%3A10470177" target="_blank" >RIV/00064203:_____/23:10470177 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21460/23:00368444 RIV/00216208:11130/23:10470177

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pLiUN5KKwj" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pLiUN5KKwj</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fped.2023.1240363" target="_blank" >10.3389/fped.2023.1240363</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Evaluation of the impact of oximeter averaging times on automated FiO(2) control in routine NICU care: a randomized cross-over study

Popis výsledku v původním jazyce

OBJECTIVE: Changes in oximeter averaging times have been noted to affect alarm settings. Automated algorithms (A-FiO(2)) assess FiO(2) faster than oximeter averaging, potentially impacting their effectiveness. METHODS: In a single NICU routinely using 15 fabian-PRICO A-FiO(2) systems, neonates were randomly exposed to SpO(2) averaging time settings switched every 12 h among short (2-4 s), medium (10 s), and long (16 s) oximeter averaging times for the entire duration of their A-FiO(2) exposure. Primary endpoints were the percent time in the set SpO(2) target range (dependent on PMA), SpO(2 )&lt; 80%, and SpO(2 )&gt; 98%, excluding FiO(2) = 0.21. RESULTS: Ten VLBW neonates were enrolled over 11 months. At entry, they were 17 days old (IQR: 14-19), with an adjusted gestational age of 29 weeks (IQR: 27-30). The study included data from 272 days of A-FiO(2) control (34% short, 32% medium, and 34% long). Respiratory support was predominantly non-invasive (53% NCPAP, 40% HFNC, and 6% NIPPV). The aggregate SpO(2) exposure levels were 67% (IQR: 55-82) in the target range, 5.4% (IQR: 2.0-10) with SpO(2 )&lt; 80%, and 1.2% (IQR: 0.4-3.1) with SpO(2 )&gt; 98%. There were no differences in the target range time between the SpO(2) averaging time settings. There were differences at the SpO(2) extremes (p &lt;= 0.001). The medium and long averaging were both lower than the short, with the difference larger than predicted. Multivariate analysis revealed that these findings were independent of subject, ventilation mode, target range, and overall stability. CONCLUSIONS: This A-FiO(2) algorithm is effective regardless of the SpO(2) averaging time setting. There is an advantage to the longer settings, which suggest an interaction with the controller.

Název v anglickém jazyce

Evaluation of the impact of oximeter averaging times on automated FiO(2) control in routine NICU care: a randomized cross-over study

Popis výsledku anglicky

OBJECTIVE: Changes in oximeter averaging times have been noted to affect alarm settings. Automated algorithms (A-FiO(2)) assess FiO(2) faster than oximeter averaging, potentially impacting their effectiveness. METHODS: In a single NICU routinely using 15 fabian-PRICO A-FiO(2) systems, neonates were randomly exposed to SpO(2) averaging time settings switched every 12 h among short (2-4 s), medium (10 s), and long (16 s) oximeter averaging times for the entire duration of their A-FiO(2) exposure. Primary endpoints were the percent time in the set SpO(2) target range (dependent on PMA), SpO(2 )&lt; 80%, and SpO(2 )&gt; 98%, excluding FiO(2) = 0.21. RESULTS: Ten VLBW neonates were enrolled over 11 months. At entry, they were 17 days old (IQR: 14-19), with an adjusted gestational age of 29 weeks (IQR: 27-30). The study included data from 272 days of A-FiO(2) control (34% short, 32% medium, and 34% long). Respiratory support was predominantly non-invasive (53% NCPAP, 40% HFNC, and 6% NIPPV). The aggregate SpO(2) exposure levels were 67% (IQR: 55-82) in the target range, 5.4% (IQR: 2.0-10) with SpO(2 )&lt; 80%, and 1.2% (IQR: 0.4-3.1) with SpO(2 )&gt; 98%. There were no differences in the target range time between the SpO(2) averaging time settings. There were differences at the SpO(2) extremes (p &lt;= 0.001). The medium and long averaging were both lower than the short, with the difference larger than predicted. Multivariate analysis revealed that these findings were independent of subject, ventilation mode, target range, and overall stability. CONCLUSIONS: This A-FiO(2) algorithm is effective regardless of the SpO(2) averaging time setting. There is an advantage to the longer settings, which suggest an interaction with the controller.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30200 - Clinical medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Pediatrics

ISSN

2296-2360

e-ISSN

2296-2360

Svazek periodika

11

Číslo periodika v rámci svazku

September

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

6

Strana od-do

1240363

Kód UT WoS článku

001078819100001

EID výsledku v databázi Scopus

2-s2.0-85173764343