Comparison of Clinical and Radiological Outcomes Between Uncemented and Cement Augmented Screws in Short Segment Hybrid Fixation of Unstable Osteoporotic Vertebral Fractures

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F26%3AW0000015" target="_blank" >RIV/00064211:_____/26:W0000015 - isvavai.cz</a>

Výsledek na webu

<a href="https://oadoi.org/10.3390/jcm15041414" target="_blank" >https://oadoi.org/10.3390/jcm15041414</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jcm15041414" target="_blank" >10.3390/jcm15041414</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of Clinical and Radiological Outcomes Between Uncemented and Cement Augmented Screws in Short Segment Hybrid Fixation of Unstable Osteoporotic Vertebral Fractures

Popis výsledku v původním jazyce

Purpose: This study aimed to compare the clinical and radiological outcomes of treating unstable osteoporotic vertebral fractures using hybrid fixation with uncemented transpedicular screws (Group A) versus polymethylmethacrylate (PMMA) cement-augmented screws (Group B). Methods: A retrospective comparative study of 55 patients treated between 01/2017 and 03/2024. Group A included 35 patients (mean age 71.22 +/- 6.12 years); Group B included 20 patients (mean age 72.9 +/- 7.75 years). Clinical outcomes were compared preoperatively, 6 weeks and 1 year after surgery. For clinical evaluation, the ODI and VAS for back pain were used. Restoration of the sagittal spinal profile was evaluated using the sagittal Cobb angle and the height of the fractured vertebral body. Results: Both groups showed significant clinical improvement in ODI and VAS scores at 6 weeks and 1 year postoperatively (p < 0.001), without significant between-group differences. The ODI changed from a preoperative value of 75.07 +/- 21.13 to 50.72 +/- 17.7 at 6 weeks postoperatively, and to 28.83 +/- 20.9 at 1 year postoperatively in Group A. In Group B, the preoperative ODI value of 66.8 +/- 14.56 changed to 47.00 +/- 11.72 at 6 weeks and to 19.8 +/- 9.15 at 1 year postoperatively The VAS decreased from 7.55 +/- 1.43 preoperatively to 3.50 +/- 1.17 at 6 weeks and to 1.52 +/- 1.18 at 1 year postoperatively in Group A, and from 7.53 +/- 1.39 preoperatively to 2.53 +/- 1.02 at 6 weeks and to 1.52 +/- 1.18 at 1 year postoperatively in Group B. In Group A, preoperative Cobb angle values of 11.01 +/- 13.85 improved to 7.33 +/- 16.17 at 6 weeks, with subsequent loss to 12.96 +/- 14.75 degrees at 1 year postoperatively. In Group B, preoperative values were 11.44 +/- 17.84, corrected to 5.16 +/- 8.33 at 6 weeks, and to 7.37 +/- 9.28 degrees at 1 year postoperatively. Conclusions: Good clinical outcomes were achieved in both evaluated groups using uncemented or cement-augmented screws, without a statistically significant difference. Differences were noted in the radiological evaluation of the success of sagittal profile correction. While both groups showed initial radiological improvement, the uncemented screw group experienced a statistically significant loss of correction at the 1-year follow-up.

Název v anglickém jazyce

Comparison of Clinical and Radiological Outcomes Between Uncemented and Cement Augmented Screws in Short Segment Hybrid Fixation of Unstable Osteoporotic Vertebral Fractures

Popis výsledku anglicky

Purpose: This study aimed to compare the clinical and radiological outcomes of treating unstable osteoporotic vertebral fractures using hybrid fixation with uncemented transpedicular screws (Group A) versus polymethylmethacrylate (PMMA) cement-augmented screws (Group B). Methods: A retrospective comparative study of 55 patients treated between 01/2017 and 03/2024. Group A included 35 patients (mean age 71.22 +/- 6.12 years); Group B included 20 patients (mean age 72.9 +/- 7.75 years). Clinical outcomes were compared preoperatively, 6 weeks and 1 year after surgery. For clinical evaluation, the ODI and VAS for back pain were used. Restoration of the sagittal spinal profile was evaluated using the sagittal Cobb angle and the height of the fractured vertebral body. Results: Both groups showed significant clinical improvement in ODI and VAS scores at 6 weeks and 1 year postoperatively (p < 0.001), without significant between-group differences. The ODI changed from a preoperative value of 75.07 +/- 21.13 to 50.72 +/- 17.7 at 6 weeks postoperatively, and to 28.83 +/- 20.9 at 1 year postoperatively in Group A. In Group B, the preoperative ODI value of 66.8 +/- 14.56 changed to 47.00 +/- 11.72 at 6 weeks and to 19.8 +/- 9.15 at 1 year postoperatively The VAS decreased from 7.55 +/- 1.43 preoperatively to 3.50 +/- 1.17 at 6 weeks and to 1.52 +/- 1.18 at 1 year postoperatively in Group A, and from 7.53 +/- 1.39 preoperatively to 2.53 +/- 1.02 at 6 weeks and to 1.52 +/- 1.18 at 1 year postoperatively in Group B. In Group A, preoperative Cobb angle values of 11.01 +/- 13.85 improved to 7.33 +/- 16.17 at 6 weeks, with subsequent loss to 12.96 +/- 14.75 degrees at 1 year postoperatively. In Group B, preoperative values were 11.44 +/- 17.84, corrected to 5.16 +/- 8.33 at 6 weeks, and to 7.37 +/- 9.28 degrees at 1 year postoperatively. Conclusions: Good clinical outcomes were achieved in both evaluated groups using uncemented or cement-augmented screws, without a statistically significant difference. Differences were noted in the radiological evaluation of the success of sagittal profile correction. While both groups showed initial radiological improvement, the uncemented screw group experienced a statistically significant loss of correction at the 1-year follow-up.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30218 - General and internal medicine

Projekt

<a href="/cs/project/NU23-10-00413" target="_blank" >NU23-10-00413: Genomické a systémově biologické profily jako klinické markery osteoporotických zlomenin obratlů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2026

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF CLINICAL MEDICINE

ISSN

—

e-ISSN

2077-0383

Svazek periodika

15

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

14

Strana od-do

-

Kód UT WoS článku

001701244400001

EID výsledku v databázi Scopus

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