Differences in the Modulation of Cortical Activity in Patients Suffering from Upper Arm Spasticity Following Stroke and Treated with Botulinum Toxin A

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F13%3A%230000437" target="_blank" >RIV/00098892:_____/13:#0000437 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15110/13:33144109 RIV/61989592:15120/13:33144109

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Differences in the Modulation of Cortical Activity in Patients Suffering from Upper Arm Spasticity Following Stroke and Treated with Botulinum Toxin A

Popis výsledku v původním jazyce

Aim: The aim of our functional magnetic resonance (fMRI) study was to localize the changes of cerebral cortex activation in stroke patients suffering from upper limb spasticity and treated with botulinum toxin A (BoNT). Materials and methodology: 34 patients suffering from upper limb post-stroke spasticity were examined; 9 of these patients were grouped into two homogenous subgroups that allowed independent further analysis. Group A consisted of four patients (2 males, 2 females; aged 25.5 +/- 3.4 years, range 22-31 years) who suffered from hand plegia. Group B consisted of five patients (4 males, 1 female; aged 67.0 +/- 11.1 years, range 54-80) who were able to perform real finger movement. The change of arm spasticity was assessed by using the modified Ashworth scale (MAS). fMRI was performed during imaginary movement (group A) or real movement of the impaired hand (group B). fMRI sessions were performed before (WO) and four weeks (W4) after BoNT treatment. Group B underwent addition

Název v anglickém jazyce

Differences in the Modulation of Cortical Activity in Patients Suffering from Upper Arm Spasticity Following Stroke and Treated with Botulinum Toxin A

Popis výsledku anglicky

Aim: The aim of our functional magnetic resonance (fMRI) study was to localize the changes of cerebral cortex activation in stroke patients suffering from upper limb spasticity and treated with botulinum toxin A (BoNT). Materials and methodology: 34 patients suffering from upper limb post-stroke spasticity were examined; 9 of these patients were grouped into two homogenous subgroups that allowed independent further analysis. Group A consisted of four patients (2 males, 2 females; aged 25.5 +/- 3.4 years, range 22-31 years) who suffered from hand plegia. Group B consisted of five patients (4 males, 1 female; aged 67.0 +/- 11.1 years, range 54-80) who were able to perform real finger movement. The change of arm spasticity was assessed by using the modified Ashworth scale (MAS). fMRI was performed during imaginary movement (group A) or real movement of the impaired hand (group B). fMRI sessions were performed before (WO) and four weeks (W4) after BoNT treatment. Group B underwent addition

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/NT13575" target="_blank" >NT13575: Změny organizace a aktivace mozkového kortexu u pacientů se spasticitou po ischemickém iktu v závislosti na léčbě botulotoxinem: fMRI studie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a slovenská neurologie a neurochirurgie

ISSN

1210-7859

e-ISSN

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Svazek periodika

76

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

175-182

Kód UT WoS článku

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EID výsledku v databázi Scopus

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