Total and high molecular weight adiponectin levels and prediction of insulin resistance

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F14%3A%230000737" target="_blank" >RIV/00098892:_____/14:#0000737 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00843989:_____/14:E0105269

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Total and high molecular weight adiponectin levels and prediction of insulin resistance

Popis výsledku v původním jazyce

Adiponectin is a key component in the interrelationship between adiposity, insulin resistance and inflammation. Concentrations of adiponectin and its high molecular oligomer have been extensively evaluated as epidemiological markers of the risk for developing insulin resistance, type 2 diabetes mellitus or metabolic syndrome. The study analyzed levels of total adiponectin and its high molecular oligomer (HMW form) in a group of 269 metabolically healthy adults and in 300 patients with type 2 diabetes mellitus. In healthy individuals, both total and HMW adiponectin levels were significantly higher than in diabetic patients. Total and HMW adiponectin levels were adequately correlated with the Homeostatic Model Assessment of Insulin Resistance index. Logistic regression analysis showed that increased levels of both total adiponectin (OR 0.598; 95% CI 0.483?0.723) and the HMW form (OR 0.360; 95% CI 0.242?0.511) are a protective factor against the development of insulin resistance. The resu

Název v anglickém jazyce

Total and high molecular weight adiponectin levels and prediction of insulin resistance

Popis výsledku anglicky

Adiponectin is a key component in the interrelationship between adiposity, insulin resistance and inflammation. Concentrations of adiponectin and its high molecular oligomer have been extensively evaluated as epidemiological markers of the risk for developing insulin resistance, type 2 diabetes mellitus or metabolic syndrome. The study analyzed levels of total adiponectin and its high molecular oligomer (HMW form) in a group of 269 metabolically healthy adults and in 300 patients with type 2 diabetes mellitus. In healthy individuals, both total and HMW adiponectin levels were significantly higher than in diabetic patients. Total and HMW adiponectin levels were adequately correlated with the Homeostatic Model Assessment of Insulin Resistance index. Logistic regression analysis showed that increased levels of both total adiponectin (OR 0.598; 95% CI 0.483?0.723) and the HMW form (OR 0.360; 95% CI 0.242?0.511) are a protective factor against the development of insulin resistance. The resu

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/NT11098" target="_blank" >NT11098: Epidemiologická studie významu proteinů tukové tkáně ve vztahu k inzulínové rezistenci</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Experimental and Clinical Cardiology

ISSN

1205-6626

e-ISSN

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Svazek periodika

20

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

CA - Kanada

Počet stran výsledku

7

Strana od-do

5618-5624

Kód UT WoS článku

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EID výsledku v databázi Scopus

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