The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F14%3A%230000799" target="_blank" >RIV/00098892:_____/14:#0000799 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients

Popis výsledku v původním jazyce

Dyslipidemias are very important risk factors for onset of atherosclerosis. Serum fibroblast growth factor 21 (FGF 21) could be a new promising marker to determine the risk of atherosclerosis. However, there is limited informatik about the relationshipsof FGF 21 and atherosclerosis in recent literature the aim of this study was to evaluace relationships of serum FGF 21 levels to intima-media thickness (IMT), as a surrogate marker of subclinical atherosclerosis manifestation, in dyslipidemic patients. We examined 155 individuals dividend into 3 groups: dyslipidemic patients with or without metabolit syndrome (MetS+, MetS-) and control. We found significantly higher serum FGF 21 levels and IMT in MetS+ group than in MetS- group (p?0,05) as well as in control (p?0,05). In MetS- group and in all dyslipidemic patients (MetS- and MetS+), IMT correlated positively with serum FGF 21 (r=0,486, r=0,573, p?0,01 both). In MetS- group, IMT was independently associate with FGF 21 (P?0,01). We verif

Název v anglickém jazyce

The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients

Popis výsledku anglicky

Dyslipidemias are very important risk factors for onset of atherosclerosis. Serum fibroblast growth factor 21 (FGF 21) could be a new promising marker to determine the risk of atherosclerosis. However, there is limited informatik about the relationshipsof FGF 21 and atherosclerosis in recent literature the aim of this study was to evaluace relationships of serum FGF 21 levels to intima-media thickness (IMT), as a surrogate marker of subclinical atherosclerosis manifestation, in dyslipidemic patients. We examined 155 individuals dividend into 3 groups: dyslipidemic patients with or without metabolit syndrome (MetS+, MetS-) and control. We found significantly higher serum FGF 21 levels and IMT in MetS+ group than in MetS- group (p?0,05) as well as in control (p?0,05). In MetS- group and in all dyslipidemic patients (MetS- and MetS+), IMT correlated positively with serum FGF 21 (r=0,486, r=0,573, p?0,01 both). In MetS- group, IMT was independently associate with FGF 21 (P?0,01). We verif

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Disease Markers

ISSN

0000-0000

e-ISSN

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Svazek periodika

1

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

01-06

Kód UT WoS článku

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EID výsledku v databázi Scopus

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