The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33151999" target="_blank" >RIV/61989592:15110/14:33151999 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients
Popis výsledku v původním jazyce
?Dyslipidemias are very important risk factors for onset of atherosclerosis. Serum fibroblast growth factor 21 (FGF 21) could be a new promising marker to determine the risk of atherosclerosis. However, there is limited informatik about the relationshipsof FGF 21 and atherosclerosis in recent literature the aim of this study was to evaluace relationships of serum FGF 21 levels to intima-media thickness (IMT), as a surrogate marker of subclinical atherosclerosis manifestation, in dyslipidemic patients.We examined 155 individuals dividend into 3 groups: dyslipidemic patients with or without metabolit syndrome (MetS+, MetS-) and control. We found significantly higher serum FGF 21 levels and IMT in MetS+ group than in MetS- group (p?0,05) as well as in control (p?0,05). In MetS- group and in all dyslipidemic patients (MetS- and MetS+), IMT correlated positively with serum FGF 21 (r=0,486, r=0,573, p?0,01 both). In MetS- group, IMT was independently associate with FGF 21 (P?0,01). We veri
Název v anglickém jazyce
The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients
Popis výsledku anglicky
?Dyslipidemias are very important risk factors for onset of atherosclerosis. Serum fibroblast growth factor 21 (FGF 21) could be a new promising marker to determine the risk of atherosclerosis. However, there is limited informatik about the relationshipsof FGF 21 and atherosclerosis in recent literature the aim of this study was to evaluace relationships of serum FGF 21 levels to intima-media thickness (IMT), as a surrogate marker of subclinical atherosclerosis manifestation, in dyslipidemic patients.We examined 155 individuals dividend into 3 groups: dyslipidemic patients with or without metabolit syndrome (MetS+, MetS-) and control. We found significantly higher serum FGF 21 levels and IMT in MetS+ group than in MetS- group (p?0,05) as well as in control (p?0,05). In MetS- group and in all dyslipidemic patients (MetS- and MetS+), IMT correlated positively with serum FGF 21 (r=0,486, r=0,573, p?0,01 both). In MetS- group, IMT was independently associate with FGF 21 (P?0,01). We veri
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
FP - Ostatní lékařské obory
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů